The antioxidant activities of several hydroxy-substituted 4-thiaflavanes, compounds 1-3, were determined by measuring their ability of inhibiting the autoxidation of styrene or cumene. On this basis, the role played by the number and position of OH groups and by the oxidation state of the S-atom was quantified and rationalized. With these data, it should be possible to optimize the structural features of these 'double-faced' antioxidants for structure-activity-relationship studies. A comparison between the kinetic data (kinh) reported in this paper and the previously reported values of the antiradical activities (SC50), measured by the DPPH- bleaching method, for 1-3 is made

Antioxidant and Antiradical Activity of Hydroxy-Substituted 4-Thiaflavanes / R. Amorati; M. G. Fumo; G. F. Pedulli; S. Menichetti; C. Pagliuca; C. Viglianisi. - In: HELVETICA CHIMICA ACTA. - ISSN 0018-019X. - STAMPA. - 89:(2006), pp. 2462-2472. [10.1002/hlca.200690226]

Antioxidant and Antiradical Activity of Hydroxy-Substituted 4-Thiaflavanes

MENICHETTI, STEFANO;VIGLIANISI, CATERINA
2006

Abstract

The antioxidant activities of several hydroxy-substituted 4-thiaflavanes, compounds 1-3, were determined by measuring their ability of inhibiting the autoxidation of styrene or cumene. On this basis, the role played by the number and position of OH groups and by the oxidation state of the S-atom was quantified and rationalized. With these data, it should be possible to optimize the structural features of these 'double-faced' antioxidants for structure-activity-relationship studies. A comparison between the kinetic data (kinh) reported in this paper and the previously reported values of the antiradical activities (SC50), measured by the DPPH- bleaching method, for 1-3 is made
2006
89
2462
2472
R. Amorati; M. G. Fumo; G. F. Pedulli; S. Menichetti; C. Pagliuca; C. Viglianisi
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/253910
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