2-arylpropionic acid esters were evaluated for their binding profile for muscarinic receptors; compounds 1 and 7 showed a good affinity for m4 receptors.
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity / C. GHELARDINI; I. MIZUMA; F. GUALTIERI; A. BARTOLINI; N. GALEOTTI; M. ROMANELLI; E. TEODORI. - In: ARZNEIMITTEL-FORSCHUNG. - ISSN 0004-4172. - STAMPA. - 49 (I):(1999), pp. 483-488.
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity
GHELARDINI, CARLA;GUALTIERI, FULVIO;BARTOLINI, ALESSANDRO;GALEOTTI, NICOLETTA;ROMANELLI, MARIA NOVELLA;TEODORI, ELISABETTA
1999
Abstract
2-arylpropionic acid esters were evaluated for their binding profile for muscarinic receptors; compounds 1 and 7 showed a good affinity for m4 receptors.
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