he use of enoxaparin as a replacement drug to standard heparin, for anticoagulation during extracorporeal circulation, in patients with heparin-induced thrombocytopenia, is still very limited. Enoxaparin significantly reduces thrombin formation and activity during cardiopulmonary bypass. The prolonged circulating rate, slow elimination rate and non-total reversion of enoxaparin by protamine can induce important postoperative bleeding. We are describing the first case of cardiac transplantation where enoxaparin was used as a replacement drug to standard heparin.
Undergoing cardiopulmonary bypass using enoxaparin only during a cardiac transplantation procedure / M. BONACCHI; E. PRIFTI; M. LEACCHE; F. MIRALDI. - In: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. - ISSN 1010-7940. - STAMPA. - 17 (6):(2000), pp. 760-762.
Undergoing cardiopulmonary bypass using enoxaparin only during a cardiac transplantation procedure
BONACCHI, MASSIMO;
2000
Abstract
he use of enoxaparin as a replacement drug to standard heparin, for anticoagulation during extracorporeal circulation, in patients with heparin-induced thrombocytopenia, is still very limited. Enoxaparin significantly reduces thrombin formation and activity during cardiopulmonary bypass. The prolonged circulating rate, slow elimination rate and non-total reversion of enoxaparin by protamine can induce important postoperative bleeding. We are describing the first case of cardiac transplantation where enoxaparin was used as a replacement drug to standard heparin.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.