Objective To examine whether the birth weight (BW) and the risks of being pre-term, low birth weight (LBW), and small for gestational age (SGA) of children with cystic fibrosis (CF) are different from nonaffected children. Study design Retrospective cohort study. We examined all the children with CF born in Tuscany, Italy, from 1991 to 2002 (n = 70) comparing them to the entire population of non-CF-affected children born in the same period (n = 290,059). Results The mean BW of newborns with CF was 246.2 g lower than the mean BW of the non-CF neonatal population (P = .0003). Children with CF had a higher risk of being born pre-term (RR 2.62, P = .001), LBW (RR 2.66, P = .0009), and SGA (RR = 1.74, P = .04) than the non-CF-affected children. The mean BW of term newborns with CF was 205.7 g lower than that of term non-CF-affected babies (P = .0002). Conclusions Our data show an association between CF and reduced BW and show a greater risk of being pre-term for babies with CF
Gestational and neonatal characteristics of children with cystic fibrosis: a cohort study / F. FESTINI; M. DE MARTINO; G. TACCETTI; T. REPETTO; S. CAMPANA; G. MERGNI; L. MARIANELLI; M. REALI. - In: THE JOURNAL OF PEDIATRICS. - ISSN 0022-3476. - STAMPA. - 147:(2005), pp. 316-320.
Gestational and neonatal characteristics of children with cystic fibrosis: a cohort study.
FESTINI, FILIPPO;DE MARTINO, MAURIZIO;
2005
Abstract
Objective To examine whether the birth weight (BW) and the risks of being pre-term, low birth weight (LBW), and small for gestational age (SGA) of children with cystic fibrosis (CF) are different from nonaffected children. Study design Retrospective cohort study. We examined all the children with CF born in Tuscany, Italy, from 1991 to 2002 (n = 70) comparing them to the entire population of non-CF-affected children born in the same period (n = 290,059). Results The mean BW of newborns with CF was 246.2 g lower than the mean BW of the non-CF neonatal population (P = .0003). Children with CF had a higher risk of being born pre-term (RR 2.62, P = .001), LBW (RR 2.66, P = .0009), and SGA (RR = 1.74, P = .04) than the non-CF-affected children. The mean BW of term newborns with CF was 205.7 g lower than that of term non-CF-affected babies (P = .0002). Conclusions Our data show an association between CF and reduced BW and show a greater risk of being pre-term for babies with CFFile | Dimensione | Formato | |
---|---|---|---|
AJPed Peso nascita.pdf
Accesso chiuso
Tipologia:
Versione finale referata (Postprint, Accepted manuscript)
Licenza:
Tutti i diritti riservati
Dimensione
114.81 kB
Formato
Adobe PDF
|
114.81 kB | Adobe PDF | Richiedi una copia |
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.