Using specific monoclonal antibodies, the authors studied the distribution of insulin growth factor-I (IGF-I) and its receptor in normal human testis by immunostaining techniques. IGF-I was preferentially localized in Sertoli cells. Less evident positivity was found in primary spermatocytes. In the interstitium some Leydig cells were positive for IGF-I. The major positivity for the IGF-I receptor was found in secondary spermatocytes and early spermatids, whereas Sertoli cells were less positive. An intense positivity was found in some Leydig cells.
Insulin-like growth factor-I (IGF-I) and IGF-I receptor in human testis: an immunohistochemical study / G.B.Vannelli; T.Barni; C.Orlando; A.Natali; M.Serio; G.C.Balboni. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - STAMPA. - 49:(1988), pp. 666-669.
Insulin-like growth factor-I (IGF-I) and IGF-I receptor in human testis: an immunohistochemical study
VANNELLI, GABRIELLA;BARNI, TULLIO;ORLANDO, CLAUDIO;NATALI, ALESSANDRO;SERIO, MARIO;BALBONI, GIUSEPPE CARLO
1988
Abstract
Using specific monoclonal antibodies, the authors studied the distribution of insulin growth factor-I (IGF-I) and its receptor in normal human testis by immunostaining techniques. IGF-I was preferentially localized in Sertoli cells. Less evident positivity was found in primary spermatocytes. In the interstitium some Leydig cells were positive for IGF-I. The major positivity for the IGF-I receptor was found in secondary spermatocytes and early spermatids, whereas Sertoli cells were less positive. An intense positivity was found in some Leydig cells.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.