Beta-aminopropionitrile (BAPN) is an inhibitor of pig plasma benzylamine oxidase. BAPN is oxidized by benzylamine oxidase. Inhibition develops in a time-dependent fashion upon incubation of BAPN with the enzyme in the absence of substrate. The product of oxidation of BAPN by benzylamine oxidase, cyanacetaldehyde, was identified and prepared by synthesis. It is an irreversible inhibitor of the enzyme.
Reaction of pig plasma benzylamine oxidase with beta-aminopropionitrile / L. Raimondi; G. Banchelli; B. Bertocci; M. Lodovici; G. Ignesti; R. Pirisino; F. Buffoni; V. Bertini; A. De Munno. - In: AGENTS AND ACTIONS. - ISSN 0065-4299. - STAMPA. - 16:(1985), pp. 95-98.
Reaction of pig plasma benzylamine oxidase with beta-aminopropionitrile.
RAIMONDI, LAURA;BANCHELLI, MARIA GRAZIA;LODOVICI, MAURA;PIRISINO, RENATO GIOVANNI PAOLO;BUFFONI, FRANCA;
1985
Abstract
Beta-aminopropionitrile (BAPN) is an inhibitor of pig plasma benzylamine oxidase. BAPN is oxidized by benzylamine oxidase. Inhibition develops in a time-dependent fashion upon incubation of BAPN with the enzyme in the absence of substrate. The product of oxidation of BAPN by benzylamine oxidase, cyanacetaldehyde, was identified and prepared by synthesis. It is an irreversible inhibitor of the enzyme.
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
