Please, sir, pull down your socks!

The present report stresses two main points. The first is the obvious, possibly negative implications of a selective, disease- oriented, physical examination, often forced by time. The second is that diseases such as KS, often perceived as typical of AIDS, can be shared by other conditions of acquired immunodeficiency, particularly organ transplants. KS is a relatively rare disease, yet it may cause additional immunosuppression, In addition, immunodeficiency can also raise the incidence of more harmful skin cancers, e.g., melanoma (Table 1), whose detection clearly relies on a careful and complete clinical skin examination.