Several tests based on semen variables have been proposed to predict the fertilization rate in the presence of male factor infertility, but their significance remains unclear. We investigated the utility of a screening test based on sperm survival (SST) to predict the outcome of in-vitro fertilization (IVF) cycles in the presence of male factor infertility. The SST was considered normal when the percentage of motile spermatozoa 24 h after oocyte insemination was > or =50%. The sperm survival test yielded abnormal results in <90% of cycles which were unsuccessful. The sensitivity of the SST was 87% and specificity 65% with a positive predictive value of 90% in the male factor group. We believe that the SST may be a useful predictor of the IVF cycle outcome and we propose its introduction into the routine preliminary evaluation of semen samples in cases of male factor infertility.

A sperm survival test and in-vitro fertilization outcome in the presence of male factor infertility / Coccia, MARIA ELISABETTA; Becattini, C.; Criscuoli, L.; Fuzzi, B.; Scarselli, Gianfranco. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - STAMPA. - 12:(1997), pp. 1969-1973.

A sperm survival test and in-vitro fertilization outcome in the presence of male factor infertility

Coccia Maria Elisabetta;Scarselli Gianfranco
1997

Abstract

Several tests based on semen variables have been proposed to predict the fertilization rate in the presence of male factor infertility, but their significance remains unclear. We investigated the utility of a screening test based on sperm survival (SST) to predict the outcome of in-vitro fertilization (IVF) cycles in the presence of male factor infertility. The SST was considered normal when the percentage of motile spermatozoa 24 h after oocyte insemination was > or =50%. The sperm survival test yielded abnormal results in <90% of cycles which were unsuccessful. The sensitivity of the SST was 87% and specificity 65% with a positive predictive value of 90% in the male factor group. We believe that the SST may be a useful predictor of the IVF cycle outcome and we propose its introduction into the routine preliminary evaluation of semen samples in cases of male factor infertility.
1997
12
1969
1973
Coccia, MARIA ELISABETTA; Becattini, C.; Criscuoli, L.; Fuzzi, B.; Scarselli, Gianfranco
File in questo prodotto:
File Dimensione Formato  
1997 Sperm survival test.pdf

accesso aperto

Tipologia: Altro
Licenza: Open Access
Dimensione 111.79 kB
Formato Adobe PDF
111.79 kB Adobe PDF

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/352940
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact