Purpose: Lennox-Gastaut syndrome (LGS) is a severe epileptic condition characterized by multiple seizure types including tonic seizures, slow spike-and-wave discharges on electroencephalography (EEG), and cognitive impairment. LGS can occur in apparently healthy subjects or in patients with preexisting brain damage. The onset peaks between 3 and 5 years of age and the prognosis is usually poor. Herein we report 13 subjects with trisomy 21 who developed LGS.
Lennox-Gastaut syndrome with late-onset and prominent reflex seizures in trisomy 21 patients / Ferlazzo E; Adjien CK; Guerrini R; Calarese T; Crespel A; Elia M; Striano P; Gelisse P; Bramanti P; di Bella P; Genton P. - In: EPILEPSIA. - ISSN 0013-9580. - STAMPA. - 50 (6):(2009), pp. 1587-1595. [10.1111/j.1528-1167.2008.01944.x]
Lennox-Gastaut syndrome with late-onset and prominent reflex seizures in trisomy 21 patients
GUERRINI, RENZO;
2009
Abstract
Purpose: Lennox-Gastaut syndrome (LGS) is a severe epileptic condition characterized by multiple seizure types including tonic seizures, slow spike-and-wave discharges on electroencephalography (EEG), and cognitive impairment. LGS can occur in apparently healthy subjects or in patients with preexisting brain damage. The onset peaks between 3 and 5 years of age and the prognosis is usually poor. Herein we report 13 subjects with trisomy 21 who developed LGS.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.