The new 7S-aminolentiginosine has been synthesized by a diastereoselective 1,3-dipolar cycloaddition strategy starting from 3,4-dihydroxylated pyrroline N-oxides derived from l-tartaric acid in thirteen steps. The intermediate 7S-azidolentiginosine undergoes efficiently copper(I)-catalysed Huisgen cycloadditions to alkynes.

Synthesis of the New 7S-Aminolentiginosine and Derivatives / F. M. Cordero; P. Bonanno; S. Neudeck; C. Vurchio; A. Brandi. - In: ADVANCED SYNTHESIS & CATALYSIS. - ISSN 1615-4150. - STAMPA. - 351:(2009), pp. 1155-1161. [10.1002/adsc.200800806]

Synthesis of the New 7S-Aminolentiginosine and Derivatives

CORDERO, FRANCA MARIA;BRANDI, ALBERTO
2009

Abstract

The new 7S-aminolentiginosine has been synthesized by a diastereoselective 1,3-dipolar cycloaddition strategy starting from 3,4-dihydroxylated pyrroline N-oxides derived from l-tartaric acid in thirteen steps. The intermediate 7S-azidolentiginosine undergoes efficiently copper(I)-catalysed Huisgen cycloadditions to alkynes.
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F. M. Cordero; P. Bonanno; S. Neudeck; C. Vurchio; A. Brandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/359140
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