The new 7S-aminolentiginosine has been synthesized by a diastereoselective 1,3-dipolar cycloaddition strategy starting from 3,4-dihydroxylated pyrroline N-oxides derived from l-tartaric acid in thirteen steps. The intermediate 7S-azidolentiginosine undergoes efficiently copper(I)-catalysed Huisgen cycloadditions to alkynes.
Synthesis of the New 7S-Aminolentiginosine and Derivatives / F. M. Cordero; P. Bonanno; S. Neudeck; C. Vurchio; A. Brandi. - In: ADVANCED SYNTHESIS & CATALYSIS. - ISSN 1615-4150. - STAMPA. - 351:(2009), pp. 1155-1161. [10.1002/adsc.200800806]
Synthesis of the New 7S-Aminolentiginosine and Derivatives
CORDERO, FRANCA MARIA;BRANDI, ALBERTO
2009
Abstract
The new 7S-aminolentiginosine has been synthesized by a diastereoselective 1,3-dipolar cycloaddition strategy starting from 3,4-dihydroxylated pyrroline N-oxides derived from l-tartaric acid in thirteen steps. The intermediate 7S-azidolentiginosine undergoes efficiently copper(I)-catalysed Huisgen cycloadditions to alkynes.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
INTER_09ASC1155HIGH-RESOL-PDF_7-N-Lentiginosine.pdf
Accesso chiuso
Tipologia:
Versione finale referata (Postprint, Accepted manuscript)
Licenza:
Tutti i diritti riservati
Dimensione
1.1 MB
Formato
Adobe PDF
|
1.1 MB | Adobe PDF | Richiedi una copia |
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
