The present invention refers to 3-aza-bicyclo[3.2.1]octane derivatives of general formula (I) their preparation, use and pharmaceutical compositions useful in the treatment of pathologies associated with microbial pathogens expressing aspartyl-protease activity.
Bicyclic peptidomimetic inhibitors of aspartyl-proteases for the treatment of infectious diseases / A. Guarna; A. Trabocchi; A. Cassone; E. Garaci; F. De Bernardis. - (2008).
Bicyclic peptidomimetic inhibitors of aspartyl-proteases for the treatment of infectious diseases
GUARNA, ANTONIO;TRABOCCHI, ANDREA;
2008
Abstract
The present invention refers to 3-aza-bicyclo[3.2.1]octane derivatives of general formula (I) their preparation, use and pharmaceutical compositions useful in the treatment of pathologies associated with microbial pathogens expressing aspartyl-protease activity.
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