A new method for protecting alcohols as tert-butyl ethers is reported. The reaction is performed in tert-butyl acetate in the presence of a catalytic amount of HClO4. The process is extremely efficient and primary and secondary alcohols as well as diols are protected under very mild conditions. Remarkably, tert-butyl acetate can be easily recovered after the workup of the reaction and recycled.

A New, practical, and efficient method for protecting alcohols as tert-butyl ethers / A.Barge; E.G.Occhiato; C.Prandi; D.Scarpi; S.Tabasso; P.Venturello. - In: SYNLETT. - ISSN 0936-5214. - STAMPA. - ...:(2010), pp. 812-816. [10.1055/s-0029-1219360]

A New, practical, and efficient method for protecting alcohols as tert-butyl ethers

OCCHIATO, ERNESTO GIOVANNI;SCARPI, DINA;
2010

Abstract

A new method for protecting alcohols as tert-butyl ethers is reported. The reaction is performed in tert-butyl acetate in the presence of a catalytic amount of HClO4. The process is extremely efficient and primary and secondary alcohols as well as diols are protected under very mild conditions. Remarkably, tert-butyl acetate can be easily recovered after the workup of the reaction and recycled.
2010
...
812
816
A.Barge; E.G.Occhiato; C.Prandi; D.Scarpi; S.Tabasso; P.Venturello
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/384490
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