Carbonylative Palladium-Catalyzed Reactions of Lactam-, Lactone-, and Thiolactone-Derived Vinyl Triflates and Phosphates for the Synthesis of N-, O-, and S-Heterocycles

A full account of our most recent studies on the chemistry of lactam-, lactone-, and thiolactone-derived vinyl triflates and phosphates is reported. In this review we focus on the use of these versatile electrophiles in Pd-catalyzed carbonylative reactions. They provide, through alkoxycarbonylation, aminocarbonylation and carbonylative Suzuki-Miyaura reactions, a straightforward and convenient access to useful intermediates for the synthesis of N-, O- and S-heterocyclic and natural compounds.