Polymicrogyria is one of the most common malformations of cortical development and is associated with a variety of clinical sequelae including epilepsy, intellectual disability, motor dysfunction and speech disturbance. It has heterogeneous clinical manifestations and imaging patterns, yet large cohort data defining the clinical and imaging spectrum and the relative frequencies of each subtype are lacking.
Clinical and imaging heterogeneity of polymicrogyria: a study of 328 patients / Leventer RJ; Jansen A; Pilz DT; Stoodley N; Marini C; Dubeau F; Malone J; Mitchell LA; Mandelstam S; Scheffer IE; Berkovic SF; Andermann F; Andermann E; Guerrini R; Dobyns WB.. - In: BRAIN. - ISSN 0006-8950. - STAMPA. - May, 133 pt 5:(2010), pp. 1415-1427. [10.1093/brain/awq078]