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EnglishThe antiphospholipid syndrome (APS) is defined by the presence of antiphospholipid antibodies (aPL), demonstrated by ELISAs for antibodies against phospholipids and associated phospholipidbinding cofactor proteins and/or a circulating lupus anticoagulant (LA) together with diverse systemic clinical manifestations such as thrombosis, and recurrent spontaneous abortions. According to the criteria set out in Sydney1 the only neurological manifestations that can be suitable as APS classification criteria are ischemic events (stroke and transient ischemic attacks). However, other neurological manifestations, including seizures in particular, have been repeatedly reported in APS patients.2 The present review will summarize recent research on the association of aPL, as well as other autoantibodies, with seizure disorders, with or without concomitant SLE.
Epilepsy as part of systemic lupus erythematosus and systemic antiphospholipid syndrome (Hughes syndrome) / Cimaz R; Meroni PL; Shoenfeld Y.. - In: LUPUS. - ISSN 0961-2033. - STAMPA. - 15:(2006), pp. 191-197. [10.1191/0961203306lu2272rr]
| Titolo: | Epilepsy as part of systemic lupus erythematosus and systemic antiphospholipid syndrome (Hughes syndrome). | |
| Autori di Ateneo: | ||
| Autori: | CIMAZ, ROLANDO; Meroni PL; Shoenfeld Y. | |
| Data di pubblicazione: | 2006 | |
| Rivista: | ||
| Volume: | 15 | |
| Pagina iniziale: | 191 | |
| Pagina finale: | 197 | |
| Abstract: | The antiphospholipid syndrome (APS) is defined by the presence of antiphospholipid antibodies (aPL), demonstrated by ELISAs for antibodies against phospholipids and associated phospholipidbinding cofactor proteins and/or a circulating lupus anticoagulant (LA) together with diverse systemic clinical manifestations such as thrombosis, and recurrent spontaneous abortions. According to the criteria set out in Sydney1 the only neurological manifestations that can be suitable as APS classification criteria are ischemic events (stroke and transient ischemic attacks). However, other neurological manifestations, including seizures in particular, have been repeatedly reported in APS patients.2 The present review will summarize recent research on the association of aPL, as well as other autoantibodies, with seizure disorders, with or without concomitant SLE. | |
| Handle: | http://hdl.handle.net/2158/387812 | |
| Appare nelle tipologie: | 1a - Articolo su rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| autoimmune epilepsy.pdf | Pdf editoriale (Version of record) | DRM non definito | Administrator |
http://hdl.handle.net/2158/387812
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