Synchronous Angiosarcoma, Melanoma and Morphea of the Breast Skin 14 years After Radiotherapy for Mammary Carcinoma

Giorgi, V. d.; Santi, R.; Grazzini, M.; Papi, F.; Gori, Alessia; Rossari, S.; Massi, Daniela; Lotti, Torello

doi:10.2340/00015555-0841

With the improvement in survival after breast cancer there has been increasing interest in the long-term effects of radiotherapy, including the development of tumours. Compared with the general population, breast cancer survivors have a 10-50% higher risk of developing a second cancer. Radiotherapy may play a role in the onset of such lesions. We describe here the case of a 68-year-old woman who developed synchronous cutaneous angiosarcoma, melanoma and morphea of the breast skin and the local area, 14 years after radiotherapy for breast carcinoma. Given the risk of post-radiation secondary primaries in breast cancer patients, long-term surveillance is necessary, with particular attention being paid to skin changes in the irradiation field. Radiation-induced morphea is a rare complication in which immunological abnormalities may stimulate malignant transformation. Long-term studies are required to clarify the pathogenesis of these rare associations.

Synchronous Angiosarcoma, Melanoma and Morphea of the Breast Skin 14 years After Radiotherapy for Mammary Carcinoma / V. d. Giorgi;R. Santi;M. Grazzini;F. Papi;A. Gori;S. Rossari;D. Massi;T. Lotti. - In: ACTA DERMATO-VENEREOLOGICA. - ISSN 0001-5555. - ELETTRONICO. - 90:(2010), pp. 283-286. [10.2340/00015555-0841]

trova@unifi

Titolo:	Synchronous Angiosarcoma, Melanoma and Morphea of the Breast Skin 14 years After Radiotherapy for Mammary Carcinoma
Autori di Ateneo:	V. d. Giorgi R. Santi M. Grazzini F. Papi GORI, ALESSIA S. Rossari MASSI, DANIELA LOTTI, TORELLO mostra contributor esterni nascondi contributor esterni
Autori:	V. d. Giorgi; R. Santi; M. Grazzini; F. Papi; GORI, ALESSIA; S. Rossari; MASSI, DANIELA; LOTTI, TORELLO
Data di pubblicazione:	2010
Rivista:	ACTA DERMATO-VENEREOLOGICA
Volume:	90
Pagina iniziale:	283
Pagina finale:	286
Abstract:	With the improvement in survival after breast cancer there has been increasing interest in the long-term effects of radiotherapy, including the development of tumours. Compared with the general population, breast cancer survivors have a 10-50% higher risk of developing a second cancer. Radiotherapy may play a role in the onset of such lesions. We describe here the case of a 68-year-old woman who developed synchronous cutaneous angiosarcoma, melanoma and morphea of the breast skin and the local area, 14 years after radiotherapy for breast carcinoma. Given the risk of post-radiation secondary primaries in breast cancer patients, long-term surveillance is necessary, with particular attention being paid to skin changes in the irradiation field. Radiation-induced morphea is a rare complication in which immunological abnormalities may stimulate malignant transformation. Long-term studies are required to clarify the pathogenesis of these rare associations.
Handle:	http://hdl.handle.net/2158/394342
Appare nelle tipologie:	1a - Articolo su rivista

File in questo prodotto:

Non ci sono file associati a questo prodotto.

Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/2158/394342

Citazioni

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.