A skeletal diversity approach starting from morpholine acetals has been achieved by tuning a three-step process from stepwise to sequential one-pot to provide diverse scaffolds containing either a 2-oxopiperazine or a diketopiperazine skeleton.
Skeletal diversity by sequential one-pot and stepwise routes using morpholine ester scaffolds / Ciofi, Leonardo; Morvillo, M.; Sladojevich, Filippo; Guarna, Antonio; Trabocchi, Andrea. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 51:(2010), pp. 6282-6285. [10.1016/j.tetlet.2010.09.103]
Skeletal diversity by sequential one-pot and stepwise routes using morpholine ester scaffolds
CIOFI, LEONARDO;SLADOJEVICH, FILIPPO;GUARNA, ANTONIO;TRABOCCHI, ANDREA
2010
Abstract
A skeletal diversity approach starting from morpholine acetals has been achieved by tuning a three-step process from stepwise to sequential one-pot to provide diverse scaffolds containing either a 2-oxopiperazine or a diketopiperazine skeleton.
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