The aim of the study was to investigate the genetic and phenotypic characteristics of MBC in a large and well characterized population-based series of 108 MBCs from Tuscany (Central Italy) and to evaluate associations between BRCA1/BRCA2 mutation status and clinical-pathological features including breast/ovarian cancer first-degree family history, tumor histology and grade, proliferative activity, estrogen/progesterone receptors (ER/PR) and epidermal growth factor receptor 2 (HER2) expression.
BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy / L. Ottini; P. Rizzolo; I. Zanna; M. Falchetti; G. Masala; K. Ceccarelli; V. Vezzosi; A. Gulino; G. giannini; S. Bianchi; F. Sera; D. Palli. - In: BREAST CANCER RESEARCH AND TREATMENT. - ISSN 0167-6806. - STAMPA. - 116:(2009), pp. 577-586. [10.1007/s10549-008-0194-z]
BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy
BIANCHI, SIMONETTA;F. Sera;
2009
Abstract
The aim of the study was to investigate the genetic and phenotypic characteristics of MBC in a large and well characterized population-based series of 108 MBCs from Tuscany (Central Italy) and to evaluate associations between BRCA1/BRCA2 mutation status and clinical-pathological features including breast/ovarian cancer first-degree family history, tumor histology and grade, proliferative activity, estrogen/progesterone receptors (ER/PR) and epidermal growth factor receptor 2 (HER2) expression.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Ottini 2009 Breast Cancer Res Treat.pdf
Accesso chiuso
Tipologia:
Versione finale referata (Postprint, Accepted manuscript)
Licenza:
Tutti i diritti riservati
Dimensione
436.9 kB
Formato
Adobe PDF
|
436.9 kB | Adobe PDF | Richiedi una copia |
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
