We introduce a new experiment, which makes use of Spin State Selective manipulations to perform sensitive and resolved through-bond correlations in organic and biological solids at high-fields and under ultra-fast MAS. The scheme is the shortest and most sensitive through-bond correlation method introduced so far in solids, yields resolved fingerprints of uniformly (13)C-labeled biomolecules, and constitutes a tool to highlight slight static structural disorder around crystallographically equivalent molecules in microcrystalline samples.
High-Resolution and Sensitivity Through-Bond Correlations in Ultra-Fast Magic Angle Spinning (MAS) Solid-State NMR / I.Bertini; L.Emsley; I.C.Felli; S.Laage; A.Lesage; J.R. Lewandowski; A.Marchetti; R.Pierattelli; G.Pintacuda. - In: CHEMICAL SCIENCE. - ISSN 2041-6520. - STAMPA. - 2:(2011), pp. 345-348. [10.1039/c0sc00397b]
High-Resolution and Sensitivity Through-Bond Correlations in Ultra-Fast Magic Angle Spinning (MAS) Solid-State NMR
BERTINI, IVANO;FELLI, ISABELLA CATERINA;PIERATTELLI, ROBERTA;
2011
Abstract
We introduce a new experiment, which makes use of Spin State Selective manipulations to perform sensitive and resolved through-bond correlations in organic and biological solids at high-fields and under ultra-fast MAS. The scheme is the shortest and most sensitive through-bond correlation method introduced so far in solids, yields resolved fingerprints of uniformly (13)C-labeled biomolecules, and constitutes a tool to highlight slight static structural disorder around crystallographically equivalent molecules in microcrystalline samples.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.