There is today a growing up interest in proton therapy for tumors treatment, because these particles permit to tightly shape the dose to the target. Anyway, the spatial accuracy of proton therapy is limited by the uncertainty in stopping power distribution, which is calculated from the photon attenuation coefficients measured by X-ray tomography. A proton computed tomography apparatus (pCT) could be used to directly measure stopping power and reduce this uncertainty. Single proton tracking is a promising way to face difficulties due to multiple Coulomb scattering. The design of a proton radiography (pCR) prototype and its practical realization are described in this paper. The prototype is based on a Si microstrip tracker to characterize particle trajectory and on a segmented YAG:Ce calorimeter to measure their residual energy. The target is to detect protons with initial kinetic energy K=250-270 MeV and with a particle rate of ~1MHz. This prototype is the first step toward the design of a complete pCT system to measure tissue electron density with an accuracy better than 1% and with a spatial resolution better than 1 mm. are also associated to INFN, sezione di Firenze. D. Lo Presti is also associated to INFN, sezione di Catania.

PROGRESS TOWARD A PROTON COMPUTED TOMOGRAPHY APPARATUS / Menichelli, David; Valentini, Samuela; Bruzzi, Mara; Bucciolini, Marta; Capineri, Lorenzo; Marrazzo, Livia; Talamonti, Cinzia; Tesi, M.; Brianzi, M.; Civinini, C.; Lo Presti, D; Candiano, G; Cirrone, Gap; Cuttone, G.; Randazzo, N.; Russo, M.; Fucile, A; Sipala, V.. - ELETTRONICO. - PROCEEDINGS OF THE 13TH ITALIAN CONFERENCE ON SENSORS AND MICROSYSTEMS:(2009), pp. 271-277. (Intervento presentato al convegno 13th Italian Conference on Sensors and Microsystems tenutosi a roma nel 19-21 febbraio 2008).

PROGRESS TOWARD A PROTON COMPUTED TOMOGRAPHY APPARATUS

MENICHELLI, DAVID;VALENTINI, SAMUELA;BRUZZI, MARA;BUCCIOLINI, MARTA;CAPINERI, LORENZO;MARRAZZO, LIVIA;TALAMONTI, CINZIA;
2009

Abstract

There is today a growing up interest in proton therapy for tumors treatment, because these particles permit to tightly shape the dose to the target. Anyway, the spatial accuracy of proton therapy is limited by the uncertainty in stopping power distribution, which is calculated from the photon attenuation coefficients measured by X-ray tomography. A proton computed tomography apparatus (pCT) could be used to directly measure stopping power and reduce this uncertainty. Single proton tracking is a promising way to face difficulties due to multiple Coulomb scattering. The design of a proton radiography (pCR) prototype and its practical realization are described in this paper. The prototype is based on a Si microstrip tracker to characterize particle trajectory and on a segmented YAG:Ce calorimeter to measure their residual energy. The target is to detect protons with initial kinetic energy K=250-270 MeV and with a particle rate of ~1MHz. This prototype is the first step toward the design of a complete pCT system to measure tissue electron density with an accuracy better than 1% and with a spatial resolution better than 1 mm. are also associated to INFN, sezione di Firenze. D. Lo Presti is also associated to INFN, sezione di Catania.
2009
13TH ITALIAN CONFERENCE ON SENSORS AND MICROSYSTEMS
13th Italian Conference on Sensors and Microsystems
roma
19-21 febbraio 2008
Menichelli, David; Valentini, Samuela; Bruzzi, Mara; Bucciolini, Marta; Capineri, Lorenzo; Marrazzo, Livia; Talamonti, Cinzia; Tesi, M.; Brianzi, M.; Civinini, C.; Lo Presti, D; Candiano, G; Cirrone, Gap; Cuttone, G.; Randazzo, N.; Russo, M.; Fucile, A; Sipala, V.
File in questo prodotto:
File Dimensione Formato  
PROGRESS_TOWARD_A_PROTON_COMPUTED_TOMOGR.pdf

Accesso chiuso

Tipologia: Pdf editoriale (Version of record)
Licenza: Tutti i diritti riservati
Dimensione 179.43 kB
Formato Adobe PDF
179.43 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/397643
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 0
social impact