We present a new extension of Gompertz law for tumour growth and anti-tumour therapy. After discussing its qualitative and analytical properties, we show, in the spirit of [16], that, like the standard Gompertz model, it is fully compatible with the two-population model of Gyllenberg and Webb, formulated in [14] in order to provide a theoretical basis to Gompertz law. Compatibility with the model proposed in [17] is also investigated. Comparisons with some experimental data confirm the practical applicability of the model. Numerical simulations about the method performance are presented.
A generalization of Gompertz law compatible with the Gillenberg-Webb model for tumour growth / D’ONOFRIO; A. FASANO; B. MONECHI.. - In: MATHEMATICAL BIOSCIENCES. - ISSN 0025-5564. - STAMPA. - 230:(2011), pp. 45-54. [10.1016/j.mbs.2011.01.001]
A generalization of Gompertz law compatible with the Gillenberg-Webb model for tumour growth
FASANO, ANTONIO;
2011
Abstract
We present a new extension of Gompertz law for tumour growth and anti-tumour therapy. After discussing its qualitative and analytical properties, we show, in the spirit of [16], that, like the standard Gompertz model, it is fully compatible with the two-population model of Gyllenberg and Webb, formulated in [14] in order to provide a theoretical basis to Gompertz law. Compatibility with the model proposed in [17] is also investigated. Comparisons with some experimental data confirm the practical applicability of the model. Numerical simulations about the method performance are presented.File | Dimensione | Formato | |
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