In recent years, research in cosmetics has developed active molecules as protective, hydrating, and antiradicals agents, favouring cell regeneration to maintain skin wellness. Up to now peptides are among the most active but unfortunately less studied active ingredients of cosmetics. Peptides as mini-proteins are able to represent the biologically active part which could be used as ingredient involved in skin processes. This is possible if the entire protein biological activity, and/or its functional tridimensional structure limiting possible toxic side-effects is maintained due to the presence of specific amino acids. Proteins communicate by peptides and also by those organic molecules present on the side chains of amino acids, the so called co- or post-translational modifications such as sugars, lipids etc. It is evident that in this context the synthesis, purification and characterisation of modified amino acids, peptides, and semi-synthetic mini-proteins by innovative methodologies will give a fundamental contribution to peptide-based cosmetics.
Cosmetics toward peptide-based cosmeceutics / A.M. Papini. - In: CHIMICA OGGI-CHEMISTRY TODAY. - ISSN 0392-839X. - STAMPA. - 28:(2010), pp. 3-4.
Cosmetics toward peptide-based cosmeceutics
PAPINI, ANNA MARIA
2010
Abstract
In recent years, research in cosmetics has developed active molecules as protective, hydrating, and antiradicals agents, favouring cell regeneration to maintain skin wellness. Up to now peptides are among the most active but unfortunately less studied active ingredients of cosmetics. Peptides as mini-proteins are able to represent the biologically active part which could be used as ingredient involved in skin processes. This is possible if the entire protein biological activity, and/or its functional tridimensional structure limiting possible toxic side-effects is maintained due to the presence of specific amino acids. Proteins communicate by peptides and also by those organic molecules present on the side chains of amino acids, the so called co- or post-translational modifications such as sugars, lipids etc. It is evident that in this context the synthesis, purification and characterisation of modified amino acids, peptides, and semi-synthetic mini-proteins by innovative methodologies will give a fundamental contribution to peptide-based cosmetics.File | Dimensione | Formato | |
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