Diversity-Oriented Synthesis (DOS) has set as a powerful methodology for drug discovery. The Build-Couple-Pair approach allows generating in few steps different chemical structure in high yields and stereoselectivity. Here are reported two examples of diversity-generating catalytic methods .
One-pot methods for step-economy generation of diversity-oriented libraries / L. Ciofi; A. Trabocchi; A. Guarna. - STAMPA. - (2011), pp. 17-17. (Intervento presentato al convegno XXXVI "A. Corbella" Summer School tenutosi a Gargnano (BS) nel 13-17 Giugno 2011).
One-pot methods for step-economy generation of diversity-oriented libraries
CIOFI, LEONARDO;TRABOCCHI, ANDREA;GUARNA, ANTONIO
2011
Abstract
Diversity-Oriented Synthesis (DOS) has set as a powerful methodology for drug discovery. The Build-Couple-Pair approach allows generating in few steps different chemical structure in high yields and stereoselectivity. Here are reported two examples of diversity-generating catalytic methods .
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