Oleuropein aglycone is able to interfere with the aggregation path of Abeta(1-42) skipping the formation of toxic oligomers. It also affects preformed fibril deposits, by reducing their density without determining the release of toxic fragments.

Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon / S.Rigacci; V.Guidotti; M.Bucciantini; D.Nichino; A.Relini; A.Berti; M.Stefani. - In: CURRENT ALZHEIMER RESEARCH. - ISSN 1567-2050. - STAMPA. - 8:(2011), pp. 841-852.

Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon

RIGACCI, STEFANIA;BUCCIANTINI, MONICA;BERTI, ANDREA;STEFANI, MASSIMO
2011

Abstract

Oleuropein aglycone is able to interfere with the aggregation path of Abeta(1-42) skipping the formation of toxic oligomers. It also affects preformed fibril deposits, by reducing their density without determining the release of toxic fragments.
2011
8
841
852
S.Rigacci; V.Guidotti; M.Bucciantini; D.Nichino; A.Relini; A.Berti; M.Stefani
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/592794
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 109
  • ???jsp.display-item.citation.isi??? 93
social impact