Salmonella bongori Provides Insights into the Evolutionof the Salmonellae

Fookes, M.; Schroeder, G. N.; Langridge, G. C.; Blondel, C. J.; Mammina, C.; Connor, T. R.; Seth Smith, H.; Vernikos, G. S.; Robinson, K. S.; Sanders, Mandy; Petty, N. K.; Kingsley, R. A.; Ba¨umler5, A. J.; Nuccio, S. P.; Contreras, I.; Santiviago, C. A.; Maskell, D.; Barrow, P.; Humphrey, T.; Nastasi, Antonino; Roberts, M.; Frankel, G.; Parkhill, J.; Dougan, G.; Thomson, N. R.

doi:10.1371/journal.ppat.1002191

The genus Salmonella contains two species, S. bongori and S. enterica. Compared to the well-studied S. enterica there is a marked lack of information regarding the genetic makeup and diversity of S. bongori. S. bongori has been found predominantly associated with cold-blooded animals, but it can infect humans. This work suggests that S. bongori has inherited the ancestral Salmonella virulence gene set, but has adapted by incorporating virulence determinants that resemble those employed by EPEC

Salmonella bongori Provides Insights into the Evolutionof the Salmonellae / M.Fookes; GN.Schroeder; GC.Langridge; CJ.Blondel; C.Mammina; TR.Connor; H.Seth-Smith; GS.Vernikos; KS.Robinson; Mandy Sanders; NK. Petty; RA.Kingsley; AJ. Ba¨umler5; S-P Nuccio; I.Contreras; CA.Santiviago; D.Maskell; P.Barrow; T.Humphrey; Nastasi, A; M.Roberts; G.Frankel; J.Parkhill; G.Dougan; N R.Thomson. - In: PLOS PATHOGENS. - ISSN 1553-7374. - ELETTRONICO. - 7:(2011), pp. 0-0. [10.1371/journal.ppat.1002191]