We read with great interest the study by Ali-Fehmi et al1 regarding the role of cyclo-oxygenase-2 (COX-2) and angiogenesis in ovarian carcinoma. In a previous analysis, we investigated the COX-2 status in relation to tumor microvessel density (MVD) analyzed with the anti-CD34 monoclonal antibody, and vascular endothelial growth factor (VEGF) expression in a series of homogeneous untreated advanced serous ovarian carcinoma patients with low and high survival rate.
Cyclooxygenase-2, angiogenesis, tumor cell proliferation, P-glycoprotein in advanced ovarian serous carcinoma / Maria Rosaria Raspollini;Gianni Amunni;Alessandro Villanucci;Gianna Baroni;Gian Luigi Taddei. - In: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. - ISSN 0002-9378. - STAMPA. - 194:(2006), pp. 1203-1203. [10.1016/j.ajog.2005.07.086]
Cyclooxygenase-2, angiogenesis, tumor cell proliferation, P-glycoprotein in advanced ovarian serous carcinoma
AMUNNI, GIANNI;TADDEI, GIAN LUIGI
2006
Abstract
We read with great interest the study by Ali-Fehmi et al1 regarding the role of cyclo-oxygenase-2 (COX-2) and angiogenesis in ovarian carcinoma. In a previous analysis, we investigated the COX-2 status in relation to tumor microvessel density (MVD) analyzed with the anti-CD34 monoclonal antibody, and vascular endothelial growth factor (VEGF) expression in a series of homogeneous untreated advanced serous ovarian carcinoma patients with low and high survival rate.
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