In previous work [l] hand-made tribenzoylcellulose (CTB) layers developed with ethanol-water and n-hexane-2-propanol mixtures were successfully used for separation of the enantiomers of aromatic alcohols. The alcohols were detected by exposing the plates to iodine vapor for 24 h. This method of visualization does not enable quantitative determination of solutes, because spot intensity quickly decreases as a consequence of iodine vaporization. The intense UV adsorption of the CTB stationary phase, on the other hand, makes it very difficult to detect analytes which adsorb in the same wavelength range. It is, therefore, of great interest to use such chiral plates for the direct resolution and quantitative determination of solutes, e.g. thiochromanol and closely related benzoins, which adsorb strongly at wavelengths where the adsorption of the stationary phase is negligible.

Quantitative Determination of Enantiomeric Alcohols by Planar Chromatography on Tribenzoylcellulose / L. Lepri; M. Del Bubba; A. Cincinelli; M. Bracciali. - In: JOURNAL OF PLANAR CHROMATOGRAPHY ‒ MODERN TLC. - ISSN 0933-4173. - STAMPA. - 15:(2002), pp. 220-222.

Quantitative Determination of Enantiomeric Alcohols by Planar Chromatography on Tribenzoylcellulose

LEPRI, LUCIANO;DEL BUBBA, MASSIMO;CINCINELLI, ALESSANDRA;
2002

Abstract

In previous work [l] hand-made tribenzoylcellulose (CTB) layers developed with ethanol-water and n-hexane-2-propanol mixtures were successfully used for separation of the enantiomers of aromatic alcohols. The alcohols were detected by exposing the plates to iodine vapor for 24 h. This method of visualization does not enable quantitative determination of solutes, because spot intensity quickly decreases as a consequence of iodine vaporization. The intense UV adsorption of the CTB stationary phase, on the other hand, makes it very difficult to detect analytes which adsorb in the same wavelength range. It is, therefore, of great interest to use such chiral plates for the direct resolution and quantitative determination of solutes, e.g. thiochromanol and closely related benzoins, which adsorb strongly at wavelengths where the adsorption of the stationary phase is negligible.
2002
15
220
222
L. Lepri; M. Del Bubba; A. Cincinelli; M. Bracciali
File in questo prodotto:
File Dimensione Formato  
JPC_15_2002_220_222.pdf

Accesso chiuso

Tipologia: Versione finale referata (Postprint, Accepted manuscript)
Licenza: Tutti i diritti riservati
Dimensione 2.31 MB
Formato Adobe PDF
2.31 MB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/647360
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 8
social impact