The solubilizing ability towards naproxen of amorphous hydroxyethyl-beta cyclodextrins with different degrees of substitution (MS 0.6, 1.0 and 1.6) was tested and compared with that of crystalline native beta-cyclodextrin. Computer aided molecular modeling was also used in the study of naproxen-cyclodextrin inclusion complexation.

PHASE-SOLUBILITY ANAIYSIS AND MOLECULAR MODELLING IN THE STUDY OF INTERACTION OF NAPROXEN WITH HYDROXYETHYL-ß-CYCIODEXTRINS / F. MELANI; P. MURA; G. BETTINETTI; F. GIORDANO. - STAMPA. - (1994), pp. 66-66. (Intervento presentato al convegno 7th INTERNATIONAL CYCLODEXTRÍN SYMPOSIUM tenutosi a Tokyo nel 25-28 aprile 1994).

PHASE-SOLUBILITY ANAIYSIS AND MOLECULAR MODELLING IN THE STUDY OF INTERACTION OF NAPROXEN WITH HYDROXYETHYL-ß-CYCIODEXTRINS

MELANI, FABRIZIO;MURA, PAOLA ANGELA;F. GIORDANO
1994

Abstract

The solubilizing ability towards naproxen of amorphous hydroxyethyl-beta cyclodextrins with different degrees of substitution (MS 0.6, 1.0 and 1.6) was tested and compared with that of crystalline native beta-cyclodextrin. Computer aided molecular modeling was also used in the study of naproxen-cyclodextrin inclusion complexation.
1994
7th International Cyclodextrin Symposium
7th INTERNATIONAL CYCLODEXTRÍN SYMPOSIUM
Tokyo
25-28 aprile 1994
F. MELANI; P. MURA; G. BETTINETTI; F. GIORDANO
4a - Articolo in atti di congresso
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/7010
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