The solubilizing ability towards naproxen of amorphous hydroxyethyl-beta cyclodextrins with different degrees of substitution (MS 0.6, 1.0 and 1.6) was tested and compared with that of crystalline native beta-cyclodextrin. Computer aided molecular modeling was also used in the study of naproxen-cyclodextrin inclusion complexation.
PHASE-SOLUBILITY ANAIYSIS AND MOLECULAR MODELLING IN THE STUDY OF INTERACTION OF NAPROXEN WITH HYDROXYETHYL-ß-CYCIODEXTRINS / F. MELANI; P. MURA; G. BETTINETTI; F. GIORDANO. - STAMPA. - (1994), pp. 66-66. ((Intervento presentato al convegno 7th INTERNATIONAL CYCLODEXTRÍN SYMPOSIUM tenutosi a Tokyo nel 25-28 aprile 1994.
Titolo: | PHASE-SOLUBILITY ANAIYSIS AND MOLECULAR MODELLING IN THE STUDY OF INTERACTION OF NAPROXEN WITH HYDROXYETHYL-ß-CYCIODEXTRINS | |
Autori di Ateneo: | ||
Autori: | MELANI, FABRIZIO; MURA, PAOLA ANGELA; G. BETTINETTI; F. GIORDANO | |
Anno di registrazione: | 1994 | |
Titolo del libro: | 7th International Cyclodextrin Symposium | |
Titolo del congresso: | 7th INTERNATIONAL CYCLODEXTRÍN SYMPOSIUM | |
Luogo del congresso: | Tokyo | |
Data del congresso: | 25-28 aprile 1994 | |
Abstract: | The solubilizing ability towards naproxen of amorphous hydroxyethyl-beta cyclodextrins with different degrees of substitution (MS 0.6, 1.0 and 1.6) was tested and compared with that of crystalline native beta-cyclodextrin. Computer aided molecular modeling was also used in the study of naproxen-cyclodextrin inclusion complexation. | |
Handle: | http://hdl.handle.net/2158/7010 | |
Appare nelle tipologie: | 4a - Articolo in atti di congresso |