Abstract The early diagnosis and evaluation of the biological consequences of alcohol abuse are reviewed in a population of 401 chronic alcoholics admitted to our Toxicological Unit from January 1973 to the end of December 1984; selected cases were treated with disulfiram implantation. The results of the study indicate that anemia with increased globular volume of erythrocytes, elevated serum γ-glutamyl-transferase activity, increased postprandial cholalemia, and increased elimination of pentane in the breath can be considered suitable markers for the early diagnosis of alcohol abuse. Disulfiram implantation significantly prolonged the abstinence duration in the treated patients.
Biological markers and therapeutic outcome in alcoholic disease: A twelve-year survey / R. Fantozzi; L. Caramelli; F. Ledda; P. Blandina. - In: KLINISCHE WOCHENSCHRIFT. - ISSN 0023-2173. - STAMPA. - 65:(1987), pp. 27-33.
Biological markers and therapeutic outcome in alcoholic disease: A twelve-year survey
FANTOZZI, ROBERTO;BLANDINA, PATRIZIO
1987
Abstract
Abstract The early diagnosis and evaluation of the biological consequences of alcohol abuse are reviewed in a population of 401 chronic alcoholics admitted to our Toxicological Unit from January 1973 to the end of December 1984; selected cases were treated with disulfiram implantation. The results of the study indicate that anemia with increased globular volume of erythrocytes, elevated serum γ-glutamyl-transferase activity, increased postprandial cholalemia, and increased elimination of pentane in the breath can be considered suitable markers for the early diagnosis of alcohol abuse. Disulfiram implantation significantly prolonged the abstinence duration in the treated patients.
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