AIM: The aim of the present explorative cross-sectional study was to evaluate the potential role of some periodontal variables in predicting sub-clinical atherosclerosis and systemic inflammation in young adults (<or=40 years) with severe periodontitis compared with healthy individuals without periodontitis. MATERIALS AND METHODS: A total of 90 systemically healthy subjects, 45 (mean age 36.35+/-3.65 years) affected by severe periodontitis (test group) and 45 individuals (mean age 33.78+/-3.28 years) without a history of periodontal disease (control group) were enrolled in the present study. Test and control groups were paired for age, gender, body mass index (BMI) and smoking habits. Carotid intima-media thickness (carotid IMT) was bilaterally assessed by ultrasonography at the level of the common carotid artery to evaluate sub-clinical atherosclerosis. Blood samples to assess inflammatory markers (leucocytes, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, total serum cholesterol, high sensitivity C-reactive protein, glucose and haemoglobin A1c% were taken. RESULTS: In periodontal patients, mean probing depth (PD) was a predictor of mean carotid IMT (P=0.0005), BMI (P=0.0002), systolic blood pressure (P=0.0300) and diastolic blood pressure (P= 0.0199). Full-mouth bleeding score (FMBS) was a predictor of C-reactive protein levels (P=0.0218). In controls, full-mouth plaque score was a predictor of glucose levels (P=0.0074) and higher FMBS of lower triglycerides levels (P=0.0312). CONCLUSION: Mean PD and FMBS may predict sub-clinical atherosclerosis and systemic inflammation in young adults with severe periodontitis.

Periodontal variables may predict sub-clinical atherosclerosis and systemic inflammation in young adults. A cross-sectional study / Cairo F;Nieri M;Gori AM;Rotundo R;Castellani S;Abbate R;Pini-Prato GP. - In: EUROPEAN JOURNAL OF ORAL IMPLANTOLOGY. - ISSN 1756-2406. - STAMPA. - 2:(2009), pp. 125-133.

Periodontal variables may predict sub-clinical atherosclerosis and systemic inflammation in young adults. A cross-sectional study.

CAIRO, FRANCESCO;GORI, ANNA MARIA;CASTELLANI, SERGIO;ABBATE, ROSANNA;PINI PRATO, GIOVAN PAOLO
2009

Abstract

AIM: The aim of the present explorative cross-sectional study was to evaluate the potential role of some periodontal variables in predicting sub-clinical atherosclerosis and systemic inflammation in young adults (
2009
2
125
133
Cairo F;Nieri M;Gori AM;Rotundo R;Castellani S;Abbate R;Pini-Prato GP
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/774134
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