CORM-3 is a CO-releasing molecule able to mimic the anti-allergic and anti-anaphylactic effects of heme oxygenase in isolated guinea pig hearts. CORM-3 was highly effective at reducing PMN-induced CD54 expression on EC. The effect was mediated by the release of CO.
Evaluation of the effects of a novel carbon monoxide releasing molecule (CORM-3) in an in vitro model of cardiovascular inflammation / A. Vannacci; C. Marzocca; L. Giannini; L. Mazzetti; S. Franchi-Micheli; P. Failli; E. Masini; R. Motterlini; PF. Mannaioni. - In: INFLAMMATION RESEARCH. - ISSN 1023-3830. - ELETTRONICO. - 55, S1:(2006), pp. 5-6.
Evaluation of the effects of a novel carbon monoxide releasing molecule (CORM-3) in an in vitro model of cardiovascular inflammation
VANNACCI, ALFREDO;GIANNINI, LUCIA;FAILLI, PAOLA;MASINI, EMANUELA;
2006
Abstract
CORM-3 is a CO-releasing molecule able to mimic the anti-allergic and anti-anaphylactic effects of heme oxygenase in isolated guinea pig hearts. CORM-3 was highly effective at reducing PMN-induced CD54 expression on EC. The effect was mediated by the release of CO.
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