BACKGROUND: Some authors affirm that vecuronium efficacy is modified by anthropometric characteristics of people. However this drug is useful in several clinical conditions, it has very few collateral effects and it is easily stored and carried. AIM OF THE WORK: To evaluate the difference in efficacy of vecuronium in Brasilian and Italian patients. PATIENTS AND SETTING: 48 patients (21 children) submitted to ophthalmological surgical procedures in San Francisco Hospital of Grajaù (Maranhao, Brazil) and in Eye Clinic of University of Florence. STATISTIC: Student "t" and chi 2 tests. MEASURES: Myorelaxation was evaluated by a clinical score of intubation, clinical evaluation of TOF response after induction of anesthesia, recovery time after decurarization. MAIN RESULTS AND CONCLUSIONS: The two adult people (Brazilian and Italian) had significantly different weight. Children had different age/weight correlation. No significant differences exist in myorelaxation evaluation. Our results don't confirm the vecuronium efficacy differences in anthropometrically different people
[Vecuronium for anesthesia in developing countries] / Di Filippo A;Linden M. - In: MINERVA ANESTESIOLOGICA. - ISSN 0375-9393. - STAMPA. - 61:(1995), pp. 381-385.
[Vecuronium for anesthesia in developing countries].
DI FILIPPO, ALESSANDRO;
1995
Abstract
BACKGROUND: Some authors affirm that vecuronium efficacy is modified by anthropometric characteristics of people. However this drug is useful in several clinical conditions, it has very few collateral effects and it is easily stored and carried. AIM OF THE WORK: To evaluate the difference in efficacy of vecuronium in Brasilian and Italian patients. PATIENTS AND SETTING: 48 patients (21 children) submitted to ophthalmological surgical procedures in San Francisco Hospital of Grajaù (Maranhao, Brazil) and in Eye Clinic of University of Florence. STATISTIC: Student "t" and chi 2 tests. MEASURES: Myorelaxation was evaluated by a clinical score of intubation, clinical evaluation of TOF response after induction of anesthesia, recovery time after decurarization. MAIN RESULTS AND CONCLUSIONS: The two adult people (Brazilian and Italian) had significantly different weight. Children had different age/weight correlation. No significant differences exist in myorelaxation evaluation. Our results don't confirm the vecuronium efficacy differences in anthropometrically different people
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