Three preterm newborns affected by congenital syphilis, born to mothers not adequately treated during pregnancy, are described. The clinical picture is characterized by a severe cholestatic hepatopathy and, in the two surviving patients, by an unusually wide ischemic-hemorrhagic lesion of the cerebral parenchyma. This lesion is probably due to a syphilitic endarteritis, and has rarely been described before in preterm infants.
Congenital syphilis: unique clinical presentation in three preterm newborns / L. Filippi; L. Serafini; C. Dani; G. Bertini; M. Pezzati; M. Tronchin; F.F. Rubaltelli. - In: JOURNAL OF PERINATAL MEDICINE. - ISSN 0300-5577. - STAMPA. - (2004), pp. 90-94.
Congenital syphilis: unique clinical presentation in three preterm newborns
DANI, CARLO;RUBALTELLI, FIRMINO FRANCESCO
2004
Abstract
Three preterm newborns affected by congenital syphilis, born to mothers not adequately treated during pregnancy, are described. The clinical picture is characterized by a severe cholestatic hepatopathy and, in the two surviving patients, by an unusually wide ischemic-hemorrhagic lesion of the cerebral parenchyma. This lesion is probably due to a syphilitic endarteritis, and has rarely been described before in preterm infants.
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