The use of injectable local anaesthetics for the treatment of severe postoperative pain is limited by the short duration of the painkilling effect. Pre-formulation studies were carried out for the development of an injectable microparticle formulation for controlled release of prilocaine, an amino-amide type local anaesthetic suitable for intravenous, subcutaneous and intramuscular administration

Selection of PLA-polymers for the development of injectable prilocaine controlled release microparticles: Usefulness of thrmal analysis / M. Bragagni; C. Beneitez; C. Martin; D. Hernàn Pérez de la Ossa; P. Mura; M.E. Gil-Alegre. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - STAMPA. - 441:(2013), pp. 468-475. [10.1016/j.ijpharm.2012.11.007]

Selection of PLA-polymers for the development of injectable prilocaine controlled release microparticles: Usefulness of thrmal analysis

BRAGAGNI, MARCO;MURA, PAOLA ANGELA;
2013

Abstract

The use of injectable local anaesthetics for the treatment of severe postoperative pain is limited by the short duration of the painkilling effect. Pre-formulation studies were carried out for the development of an injectable microparticle formulation for controlled release of prilocaine, an amino-amide type local anaesthetic suitable for intravenous, subcutaneous and intramuscular administration
2013
441
468
475
M. Bragagni; C. Beneitez; C. Martin; D. Hernàn Pérez de la Ossa; P. Mura; M.E. Gil-Alegre
File in questo prodotto:
File Dimensione Formato  
Polym microp.doc

accesso aperto

Tipologia: Altro
Licenza: Tutti i diritti riservati
Dimensione 38.15 kB
Formato Microsoft Word
38.15 kB Microsoft Word

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/794880
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 31
  • ???jsp.display-item.citation.isi??? 30
social impact