We report that fructose 2,6-bisphosphate (Fru-2,6-P2) levels in quiescent human fibroblasts stimulated with insulin treatment increase in a time- and dose-dependent manner. The biochemical role of the sugar phosphate in the cellular response to the hormone which controls carbohydrate metabolism and acts as mitogenic factor is discussed.
The effect of insulin on Fru-2,6-P2 levels in human fibroblasts / Farnararo M; Vasta V; Bruni P; D'Alessandro A.. - In: FEBS LETTERS. - ISSN 0014-5793. - STAMPA. - 171:(1984), pp. 117-120.
The effect of insulin on Fru-2,6-P2 levels in human fibroblasts.
FARNARARO, MARTA;VASTA, VALERIA MARIA;BRUNI, PAOLA;
1984
Abstract
We report that fructose 2,6-bisphosphate (Fru-2,6-P2) levels in quiescent human fibroblasts stimulated with insulin treatment increase in a time- and dose-dependent manner. The biochemical role of the sugar phosphate in the cellular response to the hormone which controls carbohydrate metabolism and acts as mitogenic factor is discussed.
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