Herpes simplex encephalitis classically involves the periventricular white matter in infants and the mesial temporal lobes, inferior frontal lobes, and insula in older children and adults. However, the increasing use of polymerase chain reaction to detect viral DNA in the cerebrospinal fluid has allowed the expansion of the spectrum of radiologic findings possibly associated with herpes simplex encephalitis. This study presents a rare case of a previously healthy infant with herpes simplex encephalitis with occipital involvement and permanent visual impairment. Possible pathogenic mechanisms are discussed.
Herpes simplex encephalitis with occipital localization in an infant: a different route of entry in the brain system? / VENTURINI E; CHIAPPINI E; FONDA C; GALLI L; DE MARTINO M. - In: PEDIATRIC NEUROLOGY. - ISSN 0887-8994. - STAMPA. - 48:(2013), pp. 463-465.
Herpes simplex encephalitis with occipital localization in an infant: a different route of entry in the brain system?
CHIAPPINI, ELENA;GALLI, LUISA;DE MARTINO, MAURIZIO
2013
Abstract
Herpes simplex encephalitis classically involves the periventricular white matter in infants and the mesial temporal lobes, inferior frontal lobes, and insula in older children and adults. However, the increasing use of polymerase chain reaction to detect viral DNA in the cerebrospinal fluid has allowed the expansion of the spectrum of radiologic findings possibly associated with herpes simplex encephalitis. This study presents a rare case of a previously healthy infant with herpes simplex encephalitis with occipital involvement and permanent visual impairment. Possible pathogenic mechanisms are discussed.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.