Poor adherence to medications is a major health concern especially among older subjects. To plan future studies to improve adherence, an epidemiological study, called "Fiesole Misurata", was conducted. The aim of the present paper was to verify the representativeness of the database in evaluating the AntiHyperTensives (AHTs)-taking behaviour.Demographic records of all subjects aged ≥65 years (n = 2,228) living in the community of Fiesole (Florence, Italy) was retrieved from the Registry Office of Fiesole Municipality. The corresponding healthcare records were obtained from administrative archives of the Local Health Authority (claim dataset). Moreover, a cohort of subjects aged ≥65 years (n = 385) living in the community was screened by means of a multidimensional geriatric evaluation (cross-sectional dataset).In claim dataset, biyearly prevalences of hospitalization for ischemic cardiomyopathy, heart failure, and stroke were 3.7, 3.0, and 3.2\%, respectively. In the cross-sectional dataset, prevalences were 11.2, 6.7, and 7.1\%, respectively. The most used drugs were angiotensin-converting enzyme inhibitors (43.6\% in the claim dataset, 45.3\% in the cross-sectional dataset) and diuretics (35.6\% and 47.0\%, respectively). Among the incident users of AHTs, 63.5\% was highly adherent (≥80\%) over the first 6 months of follow-up, while 14.3 and 22.2\% were intermediate (40-79\%) and low (<40\%) adherent. The percentage of high adherers decreased with time and reached 31.2\% at the 24th month.These findings indicate that "Fiesole Misurata" study database can be used to develop future strategies aimed at improving the adherence to AHTs in older individuals.

Representativeness of the "Fiesole Misurata" study database for use in pharmaco-epidemiological investigations on adherence to antihypertensive medications / F. Lapi;E. Lucenteforte;M. Moschini;R. Bonaiuti;M. D. Pirro;A. Barchielli;S. Benemei;M. Belladonna;N. Nesti;R. Coppini;M. Taras;A. Vannacci;A. Ungar;A. Mugelli. - In: AGING CLINICAL AND EXPERIMENTAL RESEARCH. - ISSN 1594-0667. - ELETTRONICO. - 25:(2013), pp. 433-445. [10.1007/s40520-013-0060-7]

Representativeness of the "Fiesole Misurata" study database for use in pharmaco-epidemiological investigations on adherence to antihypertensive medications

LAPI, FRANCESCO;E. Lucenteforte;MOSCHINI, MARTINA;BONAIUTI, ROBERTO;BENEMEI, SILVIA;R. Coppini;VANNACCI, ALFREDO;MUGELLI, ALESSANDRO
2013

Abstract

Poor adherence to medications is a major health concern especially among older subjects. To plan future studies to improve adherence, an epidemiological study, called "Fiesole Misurata", was conducted. The aim of the present paper was to verify the representativeness of the database in evaluating the AntiHyperTensives (AHTs)-taking behaviour.Demographic records of all subjects aged ≥65 years (n = 2,228) living in the community of Fiesole (Florence, Italy) was retrieved from the Registry Office of Fiesole Municipality. The corresponding healthcare records were obtained from administrative archives of the Local Health Authority (claim dataset). Moreover, a cohort of subjects aged ≥65 years (n = 385) living in the community was screened by means of a multidimensional geriatric evaluation (cross-sectional dataset).In claim dataset, biyearly prevalences of hospitalization for ischemic cardiomyopathy, heart failure, and stroke were 3.7, 3.0, and 3.2\%, respectively. In the cross-sectional dataset, prevalences were 11.2, 6.7, and 7.1\%, respectively. The most used drugs were angiotensin-converting enzyme inhibitors (43.6\% in the claim dataset, 45.3\% in the cross-sectional dataset) and diuretics (35.6\% and 47.0\%, respectively). Among the incident users of AHTs, 63.5\% was highly adherent (≥80\%) over the first 6 months of follow-up, while 14.3 and 22.2\% were intermediate (40-79\%) and low (<40\%) adherent. The percentage of high adherers decreased with time and reached 31.2\% at the 24th month.These findings indicate that "Fiesole Misurata" study database can be used to develop future strategies aimed at improving the adherence to AHTs in older individuals.
2013
25
433
445
F. Lapi;E. Lucenteforte;M. Moschini;R. Bonaiuti;M. D. Pirro;A. Barchielli;S. Benemei;M. Belladonna;N. Nesti;R. Coppini;M. Taras;A. Vannacci;A. Ungar;A. Mugelli
File in questo prodotto:
File Dimensione Formato  
Lapi, Aging Clin Exp Res 2013.pdf

Accesso chiuso

Descrizione: Articolo principale
Tipologia: Pdf editoriale (Version of record)
Licenza: DRM non definito
Dimensione 293.6 kB
Formato Adobe PDF
293.6 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/818111
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 6
social impact