Aim: The aim of the current study is to identify a subgroup of patients with breast cancer who have a low risk of local recurrence after conservative surgery in order to avoid radiotherapy treatment. Methods: A group of 472 patients underwent conservative surgery without radiotherapy, and it was compared to a second group of 755 patients with similar characteristics, but who had received radiotherapy treatment (RT) after conservative surgery. Results: Breast relapse's univariate analysis demonstrated statistical significance for the following factors: radiotherapy treatment, clinical. stage, pathological stage, positive axillary nodes and tumour grading. Different results were obtained studying breast relapse. In the no-RT group breast retapse was 10.6% while in the irradiated group it was 3.4%. The breast relapse incidence decreases as the age of the patients increases especially over 75 years of age. Conclusions: In conclusion, there is clinical. evidence of avoiding adjuvant radiotherapy for patients over 75 years with T1-T2 cancer treated with quadrantectomy with a clear excision margin

The management of elderly patients with T1–T2 breast cancer treated with or without radiotherapy / L. Livi;F. Paiar;E. Meldolesi;S. Bianchi;G. Cardona;L. Cataliotti;E. Crocetti;V. Distante;G. Simontacchi;S. Scoccianti;C. Talamonti;S. Pallotta;G.P. Biti. - In: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0748-7983. - STAMPA. - 31:(2005), pp. 473-478. [10.1016/j.ejso.2005.02.024]

The management of elderly patients with T1–T2 breast cancer treated with or without radiotherapy

LIVI, LORENZO;PAIAR, FABIOLA;S. Bianchi;SCOCCIANTI, SILVIA;TALAMONTI, CINZIA;PALLOTTA, STEFANIA;BITI, GIAMPAOLO
2005

Abstract

Aim: The aim of the current study is to identify a subgroup of patients with breast cancer who have a low risk of local recurrence after conservative surgery in order to avoid radiotherapy treatment. Methods: A group of 472 patients underwent conservative surgery without radiotherapy, and it was compared to a second group of 755 patients with similar characteristics, but who had received radiotherapy treatment (RT) after conservative surgery. Results: Breast relapse's univariate analysis demonstrated statistical significance for the following factors: radiotherapy treatment, clinical. stage, pathological stage, positive axillary nodes and tumour grading. Different results were obtained studying breast relapse. In the no-RT group breast retapse was 10.6% while in the irradiated group it was 3.4%. The breast relapse incidence decreases as the age of the patients increases especially over 75 years of age. Conclusions: In conclusion, there is clinical. evidence of avoiding adjuvant radiotherapy for patients over 75 years with T1-T2 cancer treated with quadrantectomy with a clear excision margin
2005
31
473
478
L. Livi;F. Paiar;E. Meldolesi;S. Bianchi;G. Cardona;L. Cataliotti;E. Crocetti;V. Distante;G. Simontacchi;S. Scoccianti;C. Talamonti;S. Pallotta;G.P. Biti
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/822535
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