Quantitative maps of the cerebral metabolic rate of glucose (CMRGlc) derived from 2-18F-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET) images are useful in brain studies, but practical methods are needed to allow their use in clinical routine. This review looks at the kinetic model at the basis of absolute quantification of CMRGlc and at the main methods for measuring CMRGlc using 18F-FDG PET, also focusing on some critical steps in the procedure.
Back to the future: the absolute quantification of cerebral metabolic rate of glucose / Valentina Berti;Eleonora Vanzi;Cristina Polito;Alberto Pupi. - In: CLINICAL AND TRANSLATIONAL IMAGING. - ISSN 2281-5872. - ELETTRONICO. - 1:(2013), pp. 289-296. [10.1007/s40336-013-0030-2]
Back to the future: the absolute quantification of cerebral metabolic rate of glucose
BERTI, VALENTINA;VANZI, ELEONORA;POLITO, CRISTINA;PUPI, ALBERTO
2013
Abstract
Quantitative maps of the cerebral metabolic rate of glucose (CMRGlc) derived from 2-18F-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET) images are useful in brain studies, but practical methods are needed to allow their use in clinical routine. This review looks at the kinetic model at the basis of absolute quantification of CMRGlc and at the main methods for measuring CMRGlc using 18F-FDG PET, also focusing on some critical steps in the procedure.
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