The interactions between a few representative gold-based drugs and hen egg white lysozyme were studied by X-ray crystallography. High resolution crystal structures solved for three metallodrug–protein adducts provide valuable insight into the molecular mechanism of these promising metal compounds and the inherent protein metalation processes.

The mode of action of anticancer gold-based drugs: a structural perspective / Luigi Messori;Federica Scaletti;Lara Massai;Maria A. Cinellu;Chiara Gabbiani;Alessandro Vergara;Antonello Merlino. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - STAMPA. - 49:(2013), pp. 10100-10102. [10.1039/c3cc46400h]

The mode of action of anticancer gold-based drugs: a structural perspective

MESSORI, LUIGI;SCALETTI, FEDERICA;MASSAI, LARA;
2013

Abstract

The interactions between a few representative gold-based drugs and hen egg white lysozyme were studied by X-ray crystallography. High resolution crystal structures solved for three metallodrug–protein adducts provide valuable insight into the molecular mechanism of these promising metal compounds and the inherent protein metalation processes.
2013
49
10100
10102
Luigi Messori;Federica Scaletti;Lara Massai;Maria A. Cinellu;Chiara Gabbiani;Alessandro Vergara;Antonello Merlino
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/824504
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