In this review we summarize the biological role of PD-1/PD-L1 on cancer by focusing our attention in the biological rationale, clinical challenges and opportunities to target the PD-1/PD-L1 axis in melanoma.
Targeting the PD1/PD-L1 axis in melanoma: Biological rationale, clinical challenges and opportunities / Barbara Merelli; Daniela Massi; Laura Cattaneo; Mario Mandalà. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - STAMPA. - 89:(2014), pp. 140-165. [10.1016/j.critrevonc.2013.08.002]
Targeting the PD1/PD-L1 axis in melanoma: Biological rationale, clinical challenges and opportunities
MASSI, DANIELA;
2014
Abstract
In this review we summarize the biological role of PD-1/PD-L1 on cancer by focusing our attention in the biological rationale, clinical challenges and opportunities to target the PD-1/PD-L1 axis in melanoma.
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