We identified a molecular signature representative of the transcriptional abnormalities of BPDCN and developed a cellular model proposing a novel therapeutic approach in the setting of this otherwise incurable disease.
Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition / Sapienza MR;Fuligni F;Agostinelli C;Tripodo C;Righi S;Laginestra MA;Pileri A Jr;Mancini M;Rossi M;Ricci F;Gazzola A;Melle F;Mannu C;Ulbar F;Arpinati M;Paulli M;Maeda T;Gibellini D;Pagano L;Pimpinelli N;Santucci M;Cerroni L;Croce CM;Facchetti F;Piccaluga PP;Pileri SA. - In: LEUKEMIA. - ISSN 0887-6924. - STAMPA. - (2014), pp. 1606-1616. [10.1038/leu.2014.64]
Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition.
PIMPINELLI, NICOLA;SANTUCCI, MARCO;
2014
Abstract
We identified a molecular signature representative of the transcriptional abnormalities of BPDCN and developed a cellular model proposing a novel therapeutic approach in the setting of this otherwise incurable disease.
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
