Freestanding lipid bilayers were challenged with 15 nm Au nanospheres either coated by a citrate layer or passivated by a protein corona. The effect of Au nanospheres on the bilayer morphology, permeability and fluidity presents strong differences or similarities, depending on the observation length scale, from the colloidal to the molecular domains. These findings suggest that the interaction between nanoparticles and lipid membranes should be conveniently treated as a multiscale phenomenon.
Interaction of nanoparticles with lipid membranes: a multiscale perspective / Costanza Montis;Daniele Maiolo;Ivano Alessandri;Paolo Bergese;Debora Berti. - In: NANOSCALE. - ISSN 2040-3364. - STAMPA. - 6:(2014), pp. 6452-6457. [10.1039/c4nr00838c]
Interaction of nanoparticles with lipid membranes: a multiscale perspective
MONTIS, COSTANZA;BERTI, DEBORA
2014
Abstract
Freestanding lipid bilayers were challenged with 15 nm Au nanospheres either coated by a citrate layer or passivated by a protein corona. The effect of Au nanospheres on the bilayer morphology, permeability and fluidity presents strong differences or similarities, depending on the observation length scale, from the colloidal to the molecular domains. These findings suggest that the interaction between nanoparticles and lipid membranes should be conveniently treated as a multiscale phenomenon.File | Dimensione | Formato | |
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