Emerging data suggest a link between vitamin D (25(OH)D) deficiency, type 2 diabetes (T2D), and visceral adiposity. The lipid accumulation product (LAP), strictly correlated with abdominal fat depots, is proposed as marker of dysfunctional adiposity. In the presence of excess weight, subjects with and without T2D frequently feature low 25(OH)D levels. Subjects with higher LAP exhibit a high risk of 25(OH)D deficiency, suggesting that dysfunctional adiposity is a worsening factor for vitamin D hypovitaminosis.
Lipid accumulation product and 25-OH-vitamin D deficiency in type 2 diabetes / Bardini G; Giannini S; Romano D; Rotella CM; Mannucci E. - In: THE REVIEW OF DIABETIC STUDIES. - ISSN 1613-6071. - ELETTRONICO. - (2013), pp. 243-251.
Lipid accumulation product and 25-OH-vitamin D deficiency in type 2 diabetes
GIANNINI, STEFANO;ROTELLA, CARLO MARIA;MANNUCCI, EDOARDO
2013
Abstract
Emerging data suggest a link between vitamin D (25(OH)D) deficiency, type 2 diabetes (T2D), and visceral adiposity. The lipid accumulation product (LAP), strictly correlated with abdominal fat depots, is proposed as marker of dysfunctional adiposity. In the presence of excess weight, subjects with and without T2D frequently feature low 25(OH)D levels. Subjects with higher LAP exhibit a high risk of 25(OH)D deficiency, suggesting that dysfunctional adiposity is a worsening factor for vitamin D hypovitaminosis.
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