This study confirms and extends previous reports that LNK mutations occur at low frequency in JAK2 negative erythrocytosis. While their clinical significance still remains to be clarified, these mutations could represent an usefull diagnostic test to reveal an underlying clonal disease in patients negative for others more frequent mutations occurring in PV.
LNK MUTATIONS IN JAK2 NEGATIVE ERYTHROCYTOSIS / Spolverini A; Pieri L; Guglielmelli P; Pancrazzi A; Fanelli T; Paoli C;Bosi A; Vannucchi AM. - STAMPA. - (2012), pp. 128-128. ( XII Congress of the Italian Society of Experimental Hematology Roma ).
LNK MUTATIONS IN JAK2 NEGATIVE ERYTHROCYTOSIS
PIERI, LISA;PANCRAZZI, ALESSANDRO;BOSI, ALBERTO;VANNUCCHI, ALESSANDRO MARIA
2012
Abstract
This study confirms and extends previous reports that LNK mutations occur at low frequency in JAK2 negative erythrocytosis. While their clinical significance still remains to be clarified, these mutations could represent an usefull diagnostic test to reveal an underlying clonal disease in patients negative for others more frequent mutations occurring in PV.
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