The invention relates to molecular assays, reagents and kit for the mutational analysis, for diagnostic and prognostic purposes, of chronic myeloproliferative disorders, a group of neoplastic pathologies of the haemopoietic system. The invention relates to the identification of nucleic acid probes labelled with fluorochrome, allowing a quantitative assessment, in a specific and sensitive way, of mutation of MPL gene sequence and quantification of the mutated alleles of the MPL gene in Genomic DNA samples from patients with chronic myeloproliferative syndrome.

MPL mutational analysis in chronic myeloproliferative disorders / Vannucchi Alessandro Maria; Pancrazi Alessandro; Guglielmelli Paola; Ponziani Vanessa. - (2007).

MPL mutational analysis in chronic myeloproliferative disorders

VANNUCCHI, ALESSANDRO MARIA;PANCRAZZI, ALESSANDRO;GUGLIELMELLI, PAOLA;
2007

Abstract

The invention relates to molecular assays, reagents and kit for the mutational analysis, for diagnostic and prognostic purposes, of chronic myeloproliferative disorders, a group of neoplastic pathologies of the haemopoietic system. The invention relates to the identification of nucleic acid probes labelled with fluorochrome, allowing a quantitative assessment, in a specific and sensitive way, of mutation of MPL gene sequence and quantification of the mutated alleles of the MPL gene in Genomic DNA samples from patients with chronic myeloproliferative syndrome.
2007
Vannucchi Alessandro Maria; Pancrazi Alessandro; Guglielmelli Paola; Ponziani Vanessa
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/966448
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