New available immunologic tests for tuberculosis (TB) diagnosis are Interferon-gamma release assay (IGRA). In adults these tests showed a higher specificity than tuberculin skin test (TST) but their superior sensitivity compared to TST sensitivity has not been proved yet. In children, interpretation of results remains disputed, especially in those <5 years. Hereby we report the most recent literature data for use and interpretation of IGRA is results in children.
[How to interpret the results of immunological tests for the diagnosis of tuberculosis in child] / Remaschi G; Chiappini E; Bonsignori F; Mazzantini R; Galli L; De Martino M. - In: MINERVA PEDIATRICA. - ISSN 0026-4946. - STAMPA. - 31:(2013), pp. 341-347.
[How to interpret the results of immunological tests for the diagnosis of tuberculosis in child].
CHIAPPINI, ELENA;GALLI, LUISA;DE MARTINO, MAURIZIO
2013
Abstract
New available immunologic tests for tuberculosis (TB) diagnosis are Interferon-gamma release assay (IGRA). In adults these tests showed a higher specificity than tuberculin skin test (TST) but their superior sensitivity compared to TST sensitivity has not been proved yet. In children, interpretation of results remains disputed, especially in those <5 years. Hereby we report the most recent literature data for use and interpretation of IGRA is results in children.
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