Over the last 50 years, the spectrum of clinical presentation of primary hyperparathyroidism (PHPT) has shifted from a symptomatic disorder, characterized by symptoms of hypercalcemia, nephrolithiasis, and overt bone disease, toward a less symptomatic or asymptomatic disorder [1]. The recognition of the asymptomatic variant of PHPT has markedly increased following the inclusion of serum calcium measurement in the multichannel biochemical screening. Parathyroidectomy (PTX) is the only definitive cure of PHPT. PTX is appropriate to consider in all patients with PHPT and should be recommended in patients with the symptomatic variant. The question of whether patients with asymptomatic PHPT should undergo surgery, as it is recommended in the symptomatic counterpart, has been the focus of four International Workshops. The latest has been held in Florence on September 19–21, 2013. The guidelines for surgery in patients with asymptomatic PHPT and monitoring for those who do not unde ...

Italian Society of Endocrinology Consensus Statement: definition, evaluation and management of patients with mild primary hyperparathyroidism / Marcocci C; Brandi ML; Scillitani A; Corbetta S; Faggiano A; Gianotti L; Migliaccio S; Minisola S.. - In: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. - ISSN 1720-8386. - ELETTRONICO. - (2015), pp. 577-593.

Italian Society of Endocrinology Consensus Statement: definition, evaluation and management of patients with mild primary hyperparathyroidism.

BRANDI, MARIA LUISA;
2015

Abstract

Over the last 50 years, the spectrum of clinical presentation of primary hyperparathyroidism (PHPT) has shifted from a symptomatic disorder, characterized by symptoms of hypercalcemia, nephrolithiasis, and overt bone disease, toward a less symptomatic or asymptomatic disorder [1]. The recognition of the asymptomatic variant of PHPT has markedly increased following the inclusion of serum calcium measurement in the multichannel biochemical screening. Parathyroidectomy (PTX) is the only definitive cure of PHPT. PTX is appropriate to consider in all patients with PHPT and should be recommended in patients with the symptomatic variant. The question of whether patients with asymptomatic PHPT should undergo surgery, as it is recommended in the symptomatic counterpart, has been the focus of four International Workshops. The latest has been held in Florence on September 19–21, 2013. The guidelines for surgery in patients with asymptomatic PHPT and monitoring for those who do not unde ...
2015
577
593
Marcocci C; Brandi ML; Scillitani A; Corbetta S; Faggiano A; Gianotti L; Migliaccio S; Minisola S.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/996807
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