| Nome |
# |
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Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human induced pluripotent stem cells, file e398c37f-00da-179a-e053-3705fe0a4cff
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607
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Mechanical and Energetic Consequences of HCM-Causing Mutations, file e398c37d-52b2-179a-e053-3705fe0a4cff
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336
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The harder the climb the better the view: The impact of substrate stiffness on cardiomyocyte fate, file e398c381-b69c-179a-e053-3705fe0a4cff
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306
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β Blockers for prevention of exercise-induced left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy, file e398c37d-4ac4-179a-e053-3705fe0a4cff
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238
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Cardiomyocyte-specific Gq signalling and arrhythmias: Novel insights from DREADD technology, file e398c37f-3dff-179a-e053-3705fe0a4cff
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229
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Comparison of long-term outcome in anthracycline-related versus idiopathic dilated cardiomyopathy: a single centre experience, file e398c37d-4d83-179a-e053-3705fe0a4cff
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213
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Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy., file e398c37a-7f40-179a-e053-3705fe0a4cff
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165
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Late sodium current inhibitors to treat exercise induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium., file e398c37d-346f-179a-e053-3705fe0a4cff
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163
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Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation., file e398c37b-b514-179a-e053-3705fe0a4cff
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157
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The relation between sarcomere energetics and the rate of isometric tension relaxation in healthy and diseased cardiac muscle, file e398c37f-06fa-179a-e053-3705fe0a4cff
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156
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Pathogenesis of hypertrophic cardiomyopathy is mutation rather than disease specific: A comparison of the cardiac troponin T E163R and R92Q mouse models, file e398c37d-1602-179a-e053-3705fe0a4cff
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154
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Advances in Stem Cell Modeling of Dystrophin-Associated Disease: Implications for the Wider World of Dilated Cardiomyopathy, file e398c37f-be3f-179a-e053-3705fe0a4cff
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144
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Atrial Remodeling in Hypertrophic Cardiomyopathy, file e398c37c-6469-179a-e053-3705fe0a4cff
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143
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Effect of troponin Ca2+ binding properties on the kinetics of myofibril force initiation and relaxation, file e398c37c-e7b1-179a-e053-3705fe0a4cff
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138
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The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM, file e398c37e-7340-179a-e053-3705fe0a4cff
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127
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Electrical defects of the transverse-axial tubular system in cardiac diseases, file e398c37d-4fb1-179a-e053-3705fe0a4cff
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123
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Regulation of intracellular Na+ in health and disease: pathophysiological mechanisms and implications for treatment, file e398c378-ee55-179a-e053-3705fe0a4cff
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117
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A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study, file e398c37e-7342-179a-e053-3705fe0a4cff
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115
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Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy: a Translational Study, file e398c37e-b9c1-179a-e053-3705fe0a4cff
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114
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Altered Ca2+ and Na+ homeostasis in human hypertrophic cardiomyopathy: Implications for arrhythmogenesis, file e398c37f-0c4c-179a-e053-3705fe0a4cff
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105
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Myocardial Dysfunction in Hypertrophic Cardiomyopathy: Primary Effects of Sarcomeric Mutations Versus Secondary EC-Coupling Remodelling, file e398c37c-5c3f-179a-e053-3705fe0a4cff
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103
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Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM, file 64fa5412-d167-40bd-a0da-09e84b46c566
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102
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The missense E258 K-MyBP-C mutation increases the energy cost of tension generation in both ventricular and atrial tissue from HCM patients, file e398c37e-caf2-179a-e053-3705fe0a4cff
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99
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Interplay between sub-cellular alterations of calcium release and T-tubular defects in cardiac diseases, file e398c37f-17b8-179a-e053-3705fe0a4cff
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97
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Real-time optical manipulation of cardiac conduction in intact hearts, file e398c380-d77c-179a-e053-3705fe0a4cff
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94
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Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy, file e398c37f-8607-179a-e053-3705fe0a4cff
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92
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The Missense E258K-MyBP-C Mutation Increases the Energy Cost of Tension Generation in Both Ventricular and Atrial Tissue from HCM Patients, file e398c37e-be0c-179a-e053-3705fe0a4cff
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91
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Impact of Mavacamten on Force Generation in Single Myofibrils from Rabbit Psoas and Human Cardiac Muscle, file e398c380-9c2c-179a-e053-3705fe0a4cff
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82
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Design of muscle contraction assist devices by liquid crystalline elastomers, file e398c37e-7e5f-179a-e053-3705fe0a4cff
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81
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Optical investigation of action potential and calcium handling maturation of hiPSC-cardiomyocytes on biomimetic substrates, file e398c37e-d068-179a-e053-3705fe0a4cff
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78
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Letter to the Editor, file e398c37e-ef1b-179a-e053-3705fe0a4cff
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75
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Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle, file e398c381-592e-179a-e053-3705fe0a4cff
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71
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Photoresponsive Polymer-Based Biomimetic Contractile Units as Building Block for Artificial Muscles, file ed4eb329-779a-4f3b-97dd-68fbd4207742
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71
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Advanced Morpho-Functional Analysis on Ventricular and Atrial Tissue Reveals Cross-Bridge Kinetics Alterations and Sarcomere Energetic Impairment in Hcm Patients, file e398c380-7a0e-179a-e053-3705fe0a4cff
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67
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Design of Biocompatible Liquid Cristal Elastomers Reproducing the Mechanical Properties of Human Cardiac Muscle, file e398c380-b1fe-179a-e053-3705fe0a4cff
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62
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T-tubule remodeling in human hypertrophic cardiomyopathy, file e398c381-5398-179a-e053-3705fe0a4cff
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62
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Beta-Blockers for Prevention of Exercise-induced Left Ventricular Outflow Obstruction in Patients with Hypertrophic Cardiomyopathy, file e398c37e-ae96-179a-e053-3705fe0a4cff
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58
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Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction, file e398c380-a820-179a-e053-3705fe0a4cff
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53
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Genotype-Driven Pathogenesis of Atrial Fibrillation in Hypertrophic Cardiomyopathy: The Case of Different TNNT2 Mutations, file e398c382-503a-179a-e053-3705fe0a4cff
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52
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Alpha and beta myosin isoforms and human atrial and ventricular contraction, file e398c381-3ae0-179a-e053-3705fe0a4cff
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50
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Time resolved depression of isometric force by Mavacamten in single myofibrils from rabbit psoas and human cardiac muscle, file e398c37e-7e64-179a-e053-3705fe0a4cff
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49
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Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms, file 17ac9e87-a5c2-41fd-9197-68a033dc4759
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47
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T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure., file e398c37b-b0ba-179a-e053-3705fe0a4cff
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47
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3D imaging and morphometry of the heart capillary system in spontaneously hypertensive rats and normotensive controls, file e398c381-2ebf-179a-e053-3705fe0a4cff
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45
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Cellular determinants of arrhythmic rysk in hypertrophic cardiomyopathy, file e398c381-e9f7-179a-e053-3705fe0a4cff
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34
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Targets for therapy in sarcomeric cardiomyopathies., file e398c378-f265-179a-e053-3705fe0a4cff
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32
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Contraction and electrophysiological abnormalities in myofilament mutation-positive and mutation-negative human HCM myocardium, file c8fdb988-c9f0-4852-a68e-c90b3b2b7131
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29
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Sealing t-tubules increases the energy cost of cardiac contraction, file 8cb88c4f-817e-44c6-b30e-1b311e99e9a4
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26
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Mavacamten depresses human atrial contractility in the same EC50% range as human ventricle, file 9bfedbd4-13df-454d-b54d-c05b99713bcc
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20
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Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair, file e398c381-e756-179a-e053-3705fe0a4cff
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20
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Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review, file 7ff42f1d-5215-4c62-88bc-fe0404b632d8
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18
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Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency, file d2f9b246-82c1-43d7-b2e0-9b25396e8443
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18
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Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair, file e398c37e-8882-179a-e053-3705fe0a4cff
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6
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Quantification of Myocyte Disarray in Human Cardiac Tissue, file 30b6647d-e24d-4467-9087-6280ba3f841a
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3
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Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair, file e398c37c-4ac1-179a-e053-3705fe0a4cff
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3
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Ranolazine prevents phenotype development in a mouse model of hypertrophic cardiomyopathy, file e398c37f-7666-179a-e053-3705fe0a4cff
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3
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EFFECTS OF CHRONIC ATRIAL FIBRILLATION ON ACTIVE AND PASSIVE FORCE GENERATION IN HUMAN ATRIAL MYOFIBRILS, file e398c378-bc15-179a-e053-3705fe0a4cff
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2
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Optogenetic confirmation of transverse‐tubular membrane excitability in intact cardiac myocytes, file a1d7f78a-d32d-4b0f-9614-9bd9ceafe5c3
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1
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Late Sodium Current Inhibition Reverses Electro-Mechanical Dysfunction in Human Hypertrophic Cardiomyopathy, file e398c378-e7f6-179a-e053-3705fe0a4cff
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1
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Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure, file e398c378-f51b-179a-e053-3705fe0a4cff
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1
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Impact of Genotype on the Occurrence of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy., file e398c37a-8013-179a-e053-3705fe0a4cff
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1
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Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations., file e398c37a-bfaa-179a-e053-3705fe0a4cff
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1
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Histopathological comparison of intramural coronary artery remodeling and myocardial fibrosis in obstructive versus end-stage hypertrophic cardiomyopathy, file e398c37e-e2aa-179a-e053-3705fe0a4cff
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1
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EFFECTS OF MAVACAMTEN, A FIRST-IN-CLASS INHIBITOR OF SARCOMERIC MYOSINS, ON THE MECHANICS OF ATRIAL AND VENTRICULAR MAMMALIAN MYOCARDIUM AND FAST SKELETAL MUSCLE, file e398c382-5cca-179a-e053-3705fe0a4cff
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1
|
| Totale |
5.799 |