Nome |
# |
Local anaesthetic activity of beta-caryophyllene., file e398c378-b1b4-179a-e053-3705fe0a4cff
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1.762
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LOCAL ANAESTHETIC ACTIVITY OF (+) AND (-) MENTHOL, file e398c378-8436-179a-e053-3705fe0a4cff
|
799
|
PIRACETAM AND ANIRACETAM ANTAGONISM OF CENTRALLY ACTIVE DRUG-INDUCED ANTINOCICEPTION, file e398c378-8446-179a-e053-3705fe0a4cff
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684
|
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer, file e398c378-d26b-179a-e053-3705fe0a4cff
|
552
|
Acetyl-l-Carnitine in the Management of Pain During Methadone Withdrawal Syndrome., file e398c378-ae4c-179a-e053-3705fe0a4cff
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542
|
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats, file e398c378-d25d-179a-e053-3705fe0a4cff
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529
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ANTINOCICEPTION INDUCED BY AMITRIPTYLINE AND IMIPRAMINE IS MEDIATED BY A2A-ADRENOCEPTORS, file e398c37a-efee-179a-e053-3705fe0a4cff
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422
|
Involvement of potassium channels in amitriptyline and clomipramine analgesia., file e398c378-9825-179a-e053-3705fe0a4cff
|
371
|
Caffeine induces central cholinergic analgesia., file e398c378-a051-179a-e053-3705fe0a4cff
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355
|
H1-receptor stimulation induces hyperalgesia through activation of the phospholipase C-PKC pathway., file e398c378-ae48-179a-e053-3705fe0a4cff
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348
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4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs, file e398c378-9834-179a-e053-3705fe0a4cff
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345
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Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity, file e398c378-9bf3-179a-e053-3705fe0a4cff
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328
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Memory facilitation with atropine: a paradoxical effect, file e398c378-a0c9-179a-e053-3705fe0a4cff
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312
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NO DEVELOPMENT OF TOLERANCE TO ANALGESIA BY REPEATED ADMINISTRATION OF H1 ANTAGONISTS, file e398c378-843d-179a-e053-3705fe0a4cff
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311
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A Prolonged Protein Kinase C-Mediated, Opioid-Related Antinociceptive Effect of St John's Wort in Mice, file e398c378-bc0f-179a-e053-3705fe0a4cff
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307
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THE ROLE OF POTASSIUM CHANNELS IN ANTIHISTAMINE ANALGESIA, file e398c378-843b-179a-e053-3705fe0a4cff
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296
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M1 receptor activation is a requirement for arecoline analgesia., file e398c378-aeb1-179a-e053-3705fe0a4cff
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279
|
Alpha-2 agonist-induced memory impairment is mediated by the alpha-2A-adrenoceptor subtype., file e398c378-93ea-179a-e053-3705fe0a4cff
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269
|
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice, file e398c378-9165-179a-e053-3705fe0a4cff
|
268
|
ANTIHISTAMINE ANTINOCICEPTION IS MEDIATED BY GI-PROTEIN ACTIVATION, file e398c378-8430-179a-e053-3705fe0a4cff
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260
|
Blockade of intracellular calcium release induces an antidepressant-like effect in the mouse forced swimming test., file e398c378-85b6-179a-e053-3705fe0a4cff
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259
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Mono- and disubstituted-3,8-diazabicyclo[3.2.1]octane derivatives as analgesics structurally related to epibatidine: synthesis, activity, and modeling., file e398c378-a216-179a-e053-3705fe0a4cff
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258
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ANTIAMNESIC ACTIVITY OF THE NICOTINIC AGONIST DBO-83 IN MICE, file e398c378-843c-179a-e053-3705fe0a4cff
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256
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Supraspinal role of protein kinase C in oxaliplatin-induced neuropathy in rat., file e398c378-b1b3-179a-e053-3705fe0a4cff
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256
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Neuropathy-induced apoptosis: Protective effect of physostigmine, file e398c37a-fbc8-179a-e053-3705fe0a4cff
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250
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ACETYL-L-CARNITINE INDUCES MUSCARINIC ANTINOCICEPTION IN MICE AND RATS, file e398c378-9275-179a-e053-3705fe0a4cff
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249
|
Prochlorperazine induces central antinociception mediated by the muscarinic system., file e398c378-9650-179a-e053-3705fe0a4cff
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249
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IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21, file e398c378-8369-179a-e053-3705fe0a4cff
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243
|
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8, file e398c378-92be-179a-e053-3705fe0a4cff
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241
|
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs., file e398c378-9574-179a-e053-3705fe0a4cff
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240
|
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents, file e398c378-93f8-179a-e053-3705fe0a4cff
|
239
|
Acetyl-L-carnitine requires phospholipase C-IP3 pathway activation to induce antinociception., file e398c378-ae49-179a-e053-3705fe0a4cff
|
223
|
An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown., file e398c378-ae3a-179a-e053-3705fe0a4cff
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215
|
5-HT1A AGONISTS INDUCE CENTRAL CHOLINERGIC ANTINOCICEPTION, file e398c378-8445-179a-e053-3705fe0a4cff
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213
|
Diphenhydramine-induced amnesia is mediated by Gi-protein activation., file e398c378-97c6-179a-e053-3705fe0a4cff
|
211
|
[(3-chlorophenyl)piperazinylpropyl]pyridazinones and analogues as potent antinociceptive agents, file e398c378-93fb-179a-e053-3705fe0a4cff
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210
|
Effect of pertussis toxin on morphine, diphenhydramine, baclofen, clomipramine and physostigmine antinociception., file e398c378-955a-179a-e053-3705fe0a4cff
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207
|
KV1.1 CHANNEL ANTISENSE ATTENUATES LEARNING AND MODULATION OF DENTATE POLYSIALYLATED NCAM, file e398c378-843e-179a-e053-3705fe0a4cff
|
202
|
ROLE OF 5-HT4 RECEPTORS IN THE MOUSE PASSIVE AVOIDANCE TEST, file e398c378-8441-179a-e053-3705fe0a4cff
|
198
|
Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice., file e398c378-ae41-179a-e053-3705fe0a4cff
|
198
|
Role of intracellular calcium in acute thermal pain perception, file e398c378-9645-179a-e053-3705fe0a4cff
|
197
|
EFFECT OF PERTUSSIS TOXIN ON BACLOFEN-AND DIPHENHYDRAMINE- INDUCED AMNESIA, file e398c378-8444-179a-e053-3705fe0a4cff
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195
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AMITRIPTYLINE AND CLOMIPRAMINE ACTIVATE GI-PROTEIN SIGNALING PATHWAY IN THE INDUCTION OF ANALGESIA, file e398c378-8442-179a-e053-3705fe0a4cff
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188
|
Effect of K+ channel modulation on mouse feeding behaviour, file e398c378-9f92-179a-e053-3705fe0a4cff
|
187
|
Ryanodine receptors are involved in muscarinic antinociception in mice., file e398c378-ae45-179a-e053-3705fe0a4cff
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186
|
Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: An antisense study., file e398c378-ae3d-179a-e053-3705fe0a4cff
|
183
|
PHARMACOLOGICAL IDENTIFICATION OF SM-21, THE NOVEL SIGMA2 ANTAGONIST, file e398c378-8443-179a-e053-3705fe0a4cff
|
180
|
ANTINOCICEPTIVE PROFILE OF THE NATURAL CHOLINESTERASE INHIBITOR HUPERZINE A, file e398c378-8433-179a-e053-3705fe0a4cff
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177
|
Inactivation of Gi proteins induces an antidepressant-like effect in the mouse forced-swimming test., file e398c378-963e-179a-e053-3705fe0a4cff
|
176
|
In vitro characterization of a novel, potent and selective M3 antagonist, file e398c378-973d-179a-e053-3705fe0a4cff
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176
|
S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo, file e398c378-937d-179a-e053-3705fe0a4cff
|
174
|
Antinociceptive property of the nicotinic agonist AG4 in rodents, file e398c378-9bf4-179a-e053-3705fe0a4cff
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174
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Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters, file e398c378-9e8e-179a-e053-3705fe0a4cff
|
169
|
Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype?, file e398c378-cf94-179a-e053-3705fe0a4cff
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164
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Pro-cognitive activity induced in the rat by low doses of R-(+)-hyoscyamine., file e398c378-aeb3-179a-e053-3705fe0a4cff
|
162
|
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9)., file e398c378-8367-179a-e053-3705fe0a4cff
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159
|
Different involvement of type 1, 2, and 3 ryanodine receptors in memory processes., file e398c378-ae3c-179a-e053-3705fe0a4cff
|
156
|
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES, file e398c378-9d5c-179a-e053-3705fe0a4cff
|
153
|
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM, file e398c378-9f5c-179a-e053-3705fe0a4cff
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140
|
Role of Gi proteins in the antidepressant-like effect of amitriptyline and clomipramine., file e398c378-ae4b-179a-e053-3705fe0a4cff
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136
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CENTRAL CHOLINERGIC CHALLENGING OF MIGRAINE BY TESTING SECOND-GENERATION ANTICHOLINESTERASE DRUG, file e398c378-9efa-179a-e053-3705fe0a4cff
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134
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EFFECT OF POTASSIUM CHANNEL MODULATORS IN MOUSE FORCED SWIMMING TEST, file e398c378-843a-179a-e053-3705fe0a4cff
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125
|
A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice., file e398c378-ae3b-179a-e053-3705fe0a4cff
|
125
|
Endogenous morphine modulates acute thermonociception in mice., file e398c378-955e-179a-e053-3705fe0a4cff
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122
|
Influence of potassium channel modulators on cognitive processes in mice, file e398c378-96c4-179a-e053-3705fe0a4cff
|
122
|
Analgesic and antineuropathic drugs acting through central cholinergic mechanisms, file e398c37a-fe04-179a-e053-3705fe0a4cff
|
121
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Loss of muscarinic antinociception by antisense inhibition of M1 receptors., file e398c378-906b-179a-e053-3705fe0a4cff
|
102
|
ROLE OF 5-HT1A RECEPTORS IN A MOUSE PASSIVE AVOIDANCE PARADIGM, file e398c378-8437-179a-e053-3705fe0a4cff
|
100
|
Blockade of clomipramine and amitriptyline analgesia by an antisense oligonucleotide to mKv1.1, a mouse Shaker-like potassium channe, file e398c378-9183-179a-e053-3705fe0a4cff
|
80
|
Reversible antisense inhibition of Shaker-like Kv1.1 potassium channel expression impairs associative memory in mouse and rat, file e398c378-9665-179a-e053-3705fe0a4cff
|
80
|
HYPOFUNCTIONALITY OF GI PROTEINS AS AETIOPHATOGENETIC MECHANISM FOR MIGRAINE AND CLUSTER HEADACHE, file e398c378-8239-179a-e053-3705fe0a4cff
|
77
|
A REDUCED FUNCTIONALITY OF GI PROTEINS AS A POSSIBLE CAUSE FOR FIBROMYALGIA, file e398c378-8431-179a-e053-3705fe0a4cff
|
77
|
Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9, file e398c378-9913-179a-e053-3705fe0a4cff
|
69
|
Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action, file e398c378-96ca-179a-e053-3705fe0a4cff
|
61
|
Alpha-2 agonits induce amnesia through activation of the Gi-protein signalling pathway., file e398c378-965b-179a-e053-3705fe0a4cff
|
57
|
Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9, file e398c378-90eb-179a-e053-3705fe0a4cff
|
56
|
ANTIAMNESIC EFFECT OF THE TWO NOVEL K-OPIOID AGONISTS, VA-100 AND VA-101, IN THE MOUSE PASSIVE AVOIDANCE TEST, file e398c378-8434-179a-e053-3705fe0a4cff
|
53
|
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS, file e398c378-9113-179a-e053-3705fe0a4cff
|
44
|
THE CENTRAL CHOLINERGIC SYSTEM HAS A ROLE IN THE ANTINOCICEPTION INDUCED IN RODENTS AND GUINEA-PIGS BY THE ANTIMIGRAINE DRUG SUMATRIPTAN, file e398c378-843f-179a-e053-3705fe0a4cff
|
40
|
Role of potassium channels in the antinociception induced by agonists of alpha2-adrenoceptors, file e398c378-9ddf-179a-e053-3705fe0a4cff
|
37
|
Differential prevention of morphine amnesia by antisense oligodeoxynucleotides directed against Gi-protein a subunits., file e398c378-9e96-179a-e053-3705fe0a4cff
|
36
|
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity, file e398c378-9ef7-179a-e053-3705fe0a4cff
|
27
|
Antagonism by piracetam of baclofen antinociception, file e398c378-cf93-179a-e053-3705fe0a4cff
|
26
|
Involvement of central cholinergic system in antinociception induced by sumatriptan in mouse., file e398c378-aeb4-179a-e053-3705fe0a4cff
|
16
|
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION., file 3bf8548c-6d55-459a-9751-4e13663e5e36
|
14
|
Baclofen antinociception is prevented by ICV injection of pertussis toxin and by an aODN to the mKv1.1 potassium channel.., file e398c378-d6a4-179a-e053-3705fe0a4cff
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11
|
A recombinant transductor-effector system: in vitro study of G inhibitor protein (G-alfa-i1)direct activators, file e398c378-9bf7-179a-e053-3705fe0a4cff
|
1
|
The neuropathy-protective agent acetyl-L-carnitine actives PKC-gamma and MAPKs in a rat model of neuropathic pain., file e398c378-a3d4-179a-e053-3705fe0a4cff
|
1
|
Piperazine derivatives possessing nootropic activity, file e398c378-cf8f-179a-e053-3705fe0a4cff
|
1
|
Totale |
19.203 |